Mininberg D T, Genvert H P
Department of Surgery, New York Hospital-Cornell Medical Center, New York.
Urology. 1989 Mar;33(3):205-8. doi: 10.1016/0090-4295(89)90392-0.
Between 1960 and 1983, 67 boys were treated for posterior urethral valves. Despite adequate valve ablation, azotemia eventually developed in 19, and they underwent permanent urinary diversion. Normal renal function was not achieved in any of these children. Diversion does not appear to have changed the natural course of their renal insufficiency, which is most likely secondary to damage incurred prior to their initial presentation. Prognostic factors useful to identify this select population are examined.
1960年至1983年间,67名男孩接受了后尿道瓣膜治疗。尽管瓣膜切除充分,但最终仍有19人出现氮质血症,并接受了永久性尿液改道。这些儿童中没有一人恢复正常肾功能。尿液改道似乎并未改变其肾功能不全的自然病程,肾功能不全很可能继发于初次就诊前遭受的损伤。本文对有助于识别这一特定人群的预后因素进行了研究。