Kroenke K, Mangelsdorff A D
Department of Medicine, Uniformed Services University of Health Sciences, Bethesda, Maryland 20814-4799.
Am J Med. 1989 Mar;86(3):262-6. doi: 10.1016/0002-9343(89)90293-3.
Many symptoms in outpatient practice are poorly understood. To determine the incidence, diagnostic findings, and outcome of 14 common symptoms, we reviewed the records of 1,000 patients followed by house staff in an internal medicine clinic over a three-year period. The following data were abstracted for each symptom: patient characteristics, symptom duration, evaluation, suspected etiology of the symptom, treatment prescribed, and outcome of the symptom. Cost estimates for diagnostic evaluation were calculated by means of the schedule of prevailing rates for Texas employed by the Civilian Health and Medical Program of the Uniformed Services for physician reimbursement.
A total of 567 new complaints of chest pain, fatigue, dizziness, headache, edema, back pain, dyspnea, insomnia, abdominal pain, numbness, impotence, weight loss, cough, and constipation were noted, with 38 percent of the patients reporting at least one symptom. Although diagnostic testing was performed in more than two thirds of the cases, an organic etiology was demonstrated in only 16 percent. The cost of discovering an organic diagnosis was high, particularly for certain symptoms, such as headache ($7,778) and back pain ($7,263). Treatment was provided for only 55 percent of the symptoms and was often ineffective. Where outcome was documented, 164 (53 percent) of 307 symptoms improved. Three favorable prognostic factors were an organic etiology (p = 0.006), a symptom duration of less than four months (p = 0.009), and a history of two or fewer symptoms (p = 0.001).
The classification, evaluation, and management of common symptoms need to be refined. Diagnostic strategies emphasizing organic causes may be inadequate.
目的、患者及方法:门诊实践中的许多症状尚未得到充分了解。为了确定14种常见症状的发病率、诊断结果及转归,我们回顾了内科门诊三年期间由住院医师随访的1000例患者的记录。针对每种症状提取了以下数据:患者特征、症状持续时间、评估、症状的疑似病因、所开的治疗方法及症状的转归。诊断评估的费用估计是根据统一服务文职人员健康和医疗计划用于医生报销的得克萨斯州现行费率表计算得出的。
共记录到567例新发的胸痛、疲劳、头晕、头痛、水肿、背痛、呼吸困难、失眠、腹痛、麻木、阳痿、体重减轻、咳嗽及便秘等症状,38%的患者报告至少有一种症状。尽管超过三分之二的病例进行了诊断检查,但仅16%的病例证实有器质性病因。发现器质性诊断的费用很高,尤其是对于某些症状,如头痛(7778美元)和背痛(7263美元)。仅55%的症状接受了治疗,且治疗往往无效。在记录了转归的病例中,307种症状中有164种(53%)有所改善。三个有利的预后因素为器质性病因(p = 0.006)、症状持续时间少于四个月(p = 0.009)以及症状数量为两种或更少(p = 0.001)。
常见症状的分类、评估及管理需要改进。强调器质性病因的诊断策略可能并不充分。