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肺炎克雷伯菌同时产生KPC和RmtG,最终目标是瑞士。

Klebsiella pneumoniae co-producing KPC and RmtG, finally targeting Switzerland.

作者信息

Mancini Stefano, Poirel Laurent, Corthesy Myriam, Greub Gilbert, Nordmann Patrice

机构信息

Emerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland; French INSERM European Unit, University of Fribourg (LEA-IAME), Fribourg, Switzerland; Swiss National Reference Center for Emerging Antibiotic Resistance, Fribourg, Switzerland..

Emerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland; French INSERM European Unit, University of Fribourg (LEA-IAME), Fribourg, Switzerland; Swiss National Reference Center for Emerging Antibiotic Resistance, Fribourg, Switzerland.

出版信息

Diagn Microbiol Infect Dis. 2018 Feb;90(2):151-152. doi: 10.1016/j.diagmicrobio.2017.10.019. Epub 2017 Nov 6.

Abstract

A carbapenem- and pan-aminoglycoside-resistant Klebsiella pneumoniae strain was isolated from a Brazilian patient hospitalized in a Swiss hospital. The clinical isolate carried genes encoding the KPC-2 carbapenemase and the RmtG 16S rRNA methyltransferase. This is the first report of a carbapenem-resistant K. pneumoniae producing RmtG in Europe.

摘要

从一名在瑞士医院住院的巴西患者身上分离出一株对碳青霉烯类和泛氨基糖苷类耐药的肺炎克雷伯菌。该临床分离株携带编码KPC-2碳青霉烯酶和RmtG 16S rRNA甲基转移酶的基因。这是欧洲首例产RmtG的耐碳青霉烯类肺炎克雷伯菌的报告。

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