Department of Pediatric Hematology, Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Department of Child Health, School of Medicine and Dentistry, College of Health Sciences, University of Ghana, Accra, Ghana.
J Pediatr. 2018 Feb;193:183-189.e2. doi: 10.1016/j.jpeds.2017.09.082. Epub 2017 Dec 1.
To use standardized bleeding questionnaires to compare the severity and patterns of epistaxis in children with a mucocutaneous bleeding disorder and control children.
The epistaxis sections of the Pediatric Bleeding Questionnaire (PBQ) administered to pediatric patients with von Willebrand disease or a platelet function disorder and healthy control children were reviewed. Scores and features of epistaxis (frequency, duration, onset, site, seasonal correlation, and need for medical/surgical intervention) were recorded. A PBQ epistaxis score ≥2 was defined as clinically significant. The Katsanis epistaxis scoring system was administered to eligible patients, ie, with ≥5 episodes of epistaxis per year.
PBQ epistaxis scores were obtained for 66 patients, median age 12 years (range 0.6-18.3 years), and 56 control children. The median PBQ epistaxis score in patients was 2 vs 0 in control children (P <.0001). All of the features of epistaxis, except spontaneous onset, occurred in a significantly greater proportion of patients than control children with epistaxis. A total of 50% of the patients were graded as having severe epistaxis by the Katsanis epistaxis scoring system, and 30 of these (91%) had a clinically significant PBQ epistaxis score.
Standardized bleeding questionnaires are useful in the assessment of epistaxis severity and pattern and may help to distinguish children with and without a mucocutaneous bleeding disorder.
使用标准化的出血问卷比较患有黏膜皮肤出血性疾病和对照儿童的鼻出血严重程度和类型。
回顾了给予患有血管性血友病或血小板功能障碍的儿科患者和健康对照儿童的小儿出血问卷（PBQ）的鼻出血部分。记录了鼻出血的评分和特征（频率、持续时间、发作、部位、季节性相关性以及对医疗/手术干预的需求）。将 PBQ 鼻出血评分≥2 定义为临床显著。向符合条件的患者（即每年≥5 次鼻出血）提供 Katsanis 鼻出血评分系统。
获得了 66 名患者（中位年龄 12 岁，范围 0.6-18.3 岁）和 56 名对照儿童的 PBQ 鼻出血评分。患者的 PBQ 鼻出血评分中位数为 2 分，对照儿童为 0 分（P<.0001）。除自发性发作外，所有鼻出血特征在患者中发生的比例均明显高于有鼻出血的对照儿童。Katsanis 鼻出血评分系统将 50%的患者评为严重鼻出血，其中 30 例（91%）有临床显著的 PBQ 鼻出血评分。
标准化出血问卷可用于评估鼻出血的严重程度和类型，有助于区分有和无黏膜皮肤出血性疾病的儿童。
