Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH.
Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH.
J Am Coll Surg. 2018 Jun;226(6):996-1003. doi: 10.1016/j.jamcollsurg.2017.10.012. Epub 2017 Nov 30.
There is a paucity of data to inform appropriate opioid prescribing for patients who are discharged after a hospital admission for a surgical procedure.
We studied 333 inpatients discharged to home after bariatric, benign foregut, liver, pancreas, ventral hernia, and colon surgery. Chronic opioid users or patients who had complications were excluded. Home opioid usage was quantified in 90% of the remaining patients by questionnaires and phone surveys.
Eighty-five percent of patients were prescribed an opioid and 38% of prescribed opioid pills were taken. Fifteen opioid pills satisfied the opioid needs of 88% of patients discharged on postoperative day (POD) 1. For patients discharged after POD 1, in multivariate analysis, the number of opioid pills used at home was associated with the number taken the day before discharge (p < 0.0001) and patient age (p = 0.006), but not the type of surgery. Forty-one percent of patients took no opioids the day before discharge, 33% took 1 to 3, and 26% took more than 4 pills. Eighty-five percent of patients' home opioid requirements would be satisfied using the following guideline: if no opioid pills are taken the day before discharge, no prescription is needed; if 1 to 3 opioid pills are taken the day before discharge, then a prescription for 15 opioid pills is given at discharge; and if 4 or more pills are taken the day before discharge, then a prescription for 30 opioid pills is given at discharge. If these guidelines were used, the number of opioid pills prescribed would decrease by 40%.
For patients admitted after surgical procedures, post-discharge opioid use is best predicted by usage the day before discharge. Use of this guideline could decrease opioid prescriptions substantially and effectively treat patients' pain.
对于因手术住院治疗后出院的患者,目前缺乏有关适当开具阿片类药物处方的相关数据。
我们研究了 333 例因减重、良性前肠、肝脏、胰腺、腹疝和结肠手术后出院的住院患者。排除慢性阿片类药物使用者或有并发症的患者。通过问卷调查和电话调查,对其余 90%的患者进行了家庭阿片类药物使用情况的量化评估。
85%的患者开具了阿片类药物处方,38%的处方阿片类药物被服用。在术后第 1 天(POD1)出院的患者中,15 片阿片类药物即可满足 88%患者的阿片类药物需求。对于 POD1 后出院的患者,多变量分析显示,家庭中使用的阿片类药物数量与出院前一天服用的数量(p<0.0001)和患者年龄(p=0.006)有关,但与手术类型无关。41%的患者在出院前一天不服用阿片类药物,33%的患者服用 1-3 片,26%的患者服用超过 4 片。如果使用以下指南,85%的患者的家庭阿片类药物需求将得到满足:如果在出院前一天不服用阿片类药物,则无需开具处方;如果在出院前一天服用 1-3 片阿片类药物,则在出院时开具 15 片阿片类药物的处方;如果在出院前一天服用 4 片或更多阿片类药物,则在出院时开具 30 片阿片类药物的处方。如果使用这些指南,开具的阿片类药物处方数量将减少 40%。
对于因手术住院治疗后出院的患者,出院后阿片类药物的使用情况可以通过出院前一天的使用情况来预测。使用这一指南可以大幅减少阿片类药物处方数量,并有效治疗患者的疼痛。