Turley K, Turley K, Ebert P A
University of California Medical Center, San Francisco 94143.
Ann Thorac Surg. 1989 Feb;47(2):278-81. doi: 10.1016/0003-4975(89)90288-9.
The use of aortic allografts in the repair of congenital cardiac lesions has increased as a result of both the advent of cryopreservation and the effects of increased donor availability secondary to infant transplantation. During the period 1986 through 1987, 38 cryopreserved aortic allografts were placed for right ventricle-pulmonary artery discontinuity. Size of the allografts ranged from 11 to 26 mm (mean size, 19 mm), and age of the patients ranged from 6 weeks to 26 years (mean age, 5 years). Twenty-one patients had primary placement of aortic allografts, and 17 underwent replacement of previous conduits. There were 5 hospital deaths (13%) overall, only 1 among the 10 patients younger than 6 months of age with truncus arteriosus, and none among the 17 patients having conduit replacement. A large conduit could be placed with a low incidence (10.5%) of postoperative hemorrhage related to the conduit. The aortic allograft is our conduit of choice for both conduit replacement and primary repair of right ventricle-pulmonary artery discontinuity.
由于低温保存技术的出现以及婴儿移植导致供体可获得性增加的影响,同种异体主动脉移植物在先天性心脏病变修复中的应用有所增加。在1986年至1987年期间,38个低温保存的同种异体主动脉移植物被用于修复右心室-肺动脉连续性中断。移植物大小从11毫米至26毫米不等(平均大小为19毫米),患者年龄从6周龄至26岁不等(平均年龄为5岁)。21例患者首次植入同种异体主动脉移植物,17例患者接受了先前管道的置换。总体有5例医院死亡(13%),在10例年龄小于6个月的动脉干患者中仅1例死亡,在17例接受管道置换的患者中无死亡病例。可以植入较大的管道,与管道相关的术后出血发生率较低(10.5%)。同种异体主动脉移植物是我们用于管道置换以及右心室-肺动脉连续性中断一期修复的首选管道。