W Guite Jessica, Sherry David D, Jarvis Esther W, O Lewen Margaret, Khan Sarosh, Wickham Kraemer Francis
Department of Anesthesiology & Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Department of Anesthesiology & Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Pain Manag. 2018 Jan;8(1):15-25. doi: 10.2217/pmt-2017-0034. Epub 2017 Dec 4.
To characterize medication use by adolescents with chronic musculoskeletal pain syndromes before an initial multidisciplinary clinic visit.
PATIENTS & METHODS: A cross-sectional sample of 120 adolescents and parents reported on standardized assessment measures, with medication use data extracted from the medical chart and categorized.
On average, 3.2 medications were reported; 70% used more than one pain-specific medication including opioids (17%), nonopioids (31%), psychotropics/neuropathics (45%) and other medications (13%). Adolescents with complex regional pain syndrome consistently reported greatest use of opioid, psychotropic/neuropathic and other pain medications. A regression model explained 17% of the variance in pain medication use. Nonpain medication use and disability contributed unique variance - pain duration and intensity did not.
Greater attention to factors contributing to prescriptive practices, medication use and long-term outcomes is warranted.
描述患有慢性肌肉骨骼疼痛综合征的青少年在首次多学科门诊就诊前的用药情况。
120名青少年及其父母组成的横断面样本报告了标准化评估指标,用药数据从病历中提取并分类。
平均报告使用3.2种药物;70%的人使用了不止一种止痛药物,包括阿片类药物(17%)、非阿片类药物(31%)、精神药物/神经病变药物(45%)和其他药物(13%)。患有复杂性区域疼痛综合征的青少年始终报告使用阿片类药物、精神药物/神经病变药物和其他止痛药物的比例最高。一个回归模型解释了止痛药物使用差异的17%。非止痛药物使用和残疾导致了独特的差异——疼痛持续时间和强度则没有。
有必要更加关注促成处方行为、药物使用和长期结果的因素。