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维持性电休克治疗的有效性和成本效益:一项镜像自然主义分析。

Effectivity and Cost-effectivity of the Maintenance Electroconvulsive Therapy: A mirror naturalistic analysis.

作者信息

Cosculluela Albert, Cobo Jesús, Martínez-Amorós Erika, Paños Montse, Santiago Angel M, Crivillés Sara, Camposo María, Oliva Joan C, Granero Albert, Palao Diego J

机构信息

Mental Health Department, Corporació Sanitària Parc Taulí. Sabadell, Barcelona, Spain.

Mental Health Department, Corporació Sanitària Parc Taulí. Sabadell, Barcelona, Spain Departament of Psichiatry and Forensic Medicine. Universitat Autònoma de Barcelona. Bellaterra, Barcelona, Spain Center of Collaborative Biomedical Research in Mental Health (CIBERSAM).

出版信息

Actas Esp Psiquiatr. 2017 Nov;45(6):257-67. Epub 2017 Nov 1.

PMID:29199760
Abstract

INTRODUCTION

Maintenance Electroconvulsive Therapy (mECT) is a biological long-term treatment in which patients receive ECT on periods from 2 to 4 weeks, during a variable period of time, usually for more than 6 months. Recent studies showed the efficacy of mECT in prevention of relapse and recurrences. Our study wants to demostrate the effectivity and cost-effectivity of this therapy in the naturalistic conditions of our area.

DESIGN

Retrospective longitudinal study, with mirror analysis in naturalistic conditions.

SUBJECTS

Patients attended at the Corporació Sanitària Parc Taulí (Sabadell, Catalonia), and included in the mECT program during more than six months. We performed diagnostic following DSM-IV criteria, subdividing the sample in three groups: patients affected of Recurrent Major Depression, Bipolar Disorder and Schizophrenia and Related Disorders.

MEASURES

Number and duration of hospitalizations for the previous three years before the beginning of mECT, compared with the same data for the next three years following the beginning of mECT. Comparative analysis of direct hospitalization costs, costs of the mECT and pharmacologic costs. Statistic: Descriptive and non- parametric tests.

RESULTS

Sample of 35 patients (1997-2008). There is a significative reduction the number of hospitalizations and days of hospitalization in the total sample and also in each of the three subgroups. The direct total cost decreased but it was only significant in the Bipolar Disorder subgroup, due to the increased pharmacological costs.

CONCLUSIONS

mECT in our area is an effective and costeffective treatment with a great impact on the reduction of clinical decline and hospitalizations.

摘要

引言

维持性电休克治疗(mECT)是一种生物长期治疗方法,在此期间患者每2至4周接受一次电休克治疗,持续一段可变的时间,通常超过6个月。最近的研究表明mECT在预防复发方面具有疗效。我们的研究旨在证明这种疗法在我们地区实际情况下的有效性和成本效益。

设计

回顾性纵向研究,在实际情况下进行镜像分析。

研究对象

在Corporació Sanitària Parc Taulí(萨瓦德尔,加泰罗尼亚)就诊并纳入mECT计划超过六个月的患者。我们按照《精神疾病诊断与统计手册》第四版(DSM-IV)标准进行诊断,将样本分为三组:复发性重度抑郁症患者、双相情感障碍患者以及精神分裂症及相关障碍患者。

测量指标

比较mECT开始前三年的住院次数和住院时长,以及mECT开始后接下来三年的相同数据。对直接住院费用、mECT费用和药物费用进行比较分析。统计方法:描述性和非参数检验。

结果

35例患者的样本(1997 - 2008年)。总样本以及三个亚组中的每一组的住院次数和住院天数均有显著减少。直接总成本有所下降,但仅在双相情感障碍亚组中显著,原因是药物成本增加。

结论

我们地区的mECT是一种有效且具有成本效益的治疗方法,对减少临床衰退和住院次数有很大影响。

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Actas Esp Psiquiatr. 2017 Nov;45(6):257-67. Epub 2017 Nov 1.
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