Markand O N, Farlow M R, Stevens J C, Edwards M K
Department of Neurology, Indiana University School of Medicine, Indianapolis.
Arch Neurol. 1989 Mar;46(3):295-9. doi: 10.1001/archneur.1989.00520390061017.
We correlated the brain-stem auditory evoked potential (BAEP) abnormalities in 24 patients with discrete unilateral brain-stem lesions demonstrated by magnetic resonance imaging. In 18 patients who had BAEP abnormalities either confined to or more severe on stimulation of one ear, the lesion on magnetic resonance imaging was in the brain stem ipsilateral to the corresponding ear. Mesencephalic lesions produced amplitude abnormalities of the IV/V complex while pontine lesions resulted in abnormalities of earlier components (wave II and/or III). Prolongation of the I-III interpeak latency tended to occur with pontine lesions and of the III-V interpeak latency with mesencephalic lesions. Unilateral brain-stem lesions, particularly at the mesencephalic level, often produced BAEP abnormalities on both ipsilateral and contralateral monaural stimulation.
我们将24例经磁共振成像证实为单侧脑干离散性病变患者的脑干听觉诱发电位（BAEP）异常情况进行了相关性分析。在18例BAEP异常局限于或在刺激一侧耳朵时更严重的患者中，磁共振成像显示的病变位于与相应耳朵同侧的脑干。中脑病变导致IV/V复合波的波幅异常，而脑桥病变则导致早期成分（波II和/或波III）异常。I-III峰间期延长倾向于发生在脑桥病变时，而III-V峰间期延长则发生在中脑病变时。单侧脑干病变，尤其是中脑水平的病变，在同侧和对侧单耳刺激时常常会导致BAEP异常。
