From the Department of General Anesthesia, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland Clinic, Cleveland, Ohio.
Department of Anesthesiology, Mayo Clinic College of Medicine, Jacksonville, Florida.
Anesth Analg. 2018 Jul;127(1):71-80. doi: 10.1213/ANE.0000000000002670.
A panel of clinician scientists with expertise in neuromuscular blockade (NMB) monitoring was convened with a charge to prepare a consensus statement on indications for and proper use of such monitors. The aims of this article are to: (a) provide the rationale and scientific basis for the use of quantitative NMB monitoring; (b) offer a set of recommendations for quantitative NMB monitoring standards; (c) specify educational goals; and (d) propose training recommendations to ensure proper neuromuscular monitoring and management. The panel believes that whenever a neuromuscular blocker is administered, neuromuscular function must be monitored by observing the evoked muscular response to peripheral nerve stimulation. Ideally, this should be done at the hand muscles (not the facial muscles) with a quantitative (objective) monitor. Objective monitoring (documentation of train-of-four ratio ≥0.90) is the only method of assuring that satisfactory recovery of neuromuscular function has taken place. The panel also recommends that subjective evaluation of the responses to train-of-four stimulation (when using a peripheral nerve stimulator) or clinical tests of recovery from NMB (such as the 5-second head lift) should be abandoned in favor of objective monitoring. During an interim period for establishing these recommendations, if only a peripheral nerve stimulator is available, its use should be mandatory in any patient receiving a neuromuscular blocking drug. The panel acknowledges that publishing this statement per se will not result in its spontaneous acceptance, adherence to its recommendations, or change in routine practice. Implementation of objective monitoring will likely require professional societies and anesthesia department leadership to champion its use to change anesthesia practitioner behavior.
一个由在神经肌肉阻滞(NMB)监测方面具有专业知识的临床科学家小组被召集在一起,负责编写一份关于使用此类监测器的适应症和正确使用方法的共识声明。本文的目的是:(a)为使用定量 NMB 监测提供原理和科学依据;(b)提出一组定量 NMB 监测标准的建议;(c)明确教育目标;以及(d)提出培训建议,以确保正确的神经肌肉监测和管理。专家组认为,只要使用神经肌肉阻滞剂,就必须通过观察周围神经刺激引起的肌肉诱发反应来监测神经肌肉功能。理想情况下,这应在手肌肉(而非面部肌肉)上使用定量(客观)监测器进行。客观监测(记录四串比≥0.90)是确保神经肌肉功能已充分恢复的唯一方法。专家组还建议,放弃对四串刺激反应的主观评估(当使用周围神经刺激器时)或对 NMB 恢复的临床测试(如 5 秒抬头试验),转而采用客观监测。在建立这些建议的过渡期间,如果仅有一种周围神经刺激器可用,则在任何接受神经肌肉阻滞剂的患者中都必须强制性使用。专家组承认,发表这份声明本身并不会导致其自动被接受、遵守其建议或改变常规做法。实施客观监测可能需要专业学会和麻醉科领导层倡导其使用,以改变麻醉医生的行为。