Lyu Shanshan, Fang Jing, Duan Tianyu, Fu Linglan, Liu Junqiu, Li Hongbin
Department of Chemistry, University of British Columbia, Vancouver, BC V6T 1Z1, Canada.
Chem Commun (Camb). 2017 Dec 14;53(100):13375-13378. doi: 10.1039/c7cc06991j.
Exploiting the optically controlled association and dissociation behavior of a photoswitchable fluorescent protein, Dronpa145N, here we demonstrate the engineering of an optically switchable reversible protein hydrogel using Dronpa145N-based protein building blocks. Our results open the possibility to optically tune the mechanical, chemical and structural properties of protein hydrogels.
利用光开关荧光蛋白Dronpa145N的光控缔合和解离行为，我们在此展示了使用基于Dronpa145N的蛋白质构建块构建光开关可逆蛋白质水凝胶的方法。我们的结果为光调控蛋白质水凝胶的机械、化学和结构性质开辟了可能性。
