Cianci Paola, Luini Chiara, Marinoni Maddalena, Nespoli Luigi, Salvatoni Alessandro, Salvatore Silvia
a Pediatric Department , University of Insubria, Ospedale "F. Del Ponte" Varese , Italy.
Pediatr Hematol Oncol. 2017 Aug;34(5):343-347. doi: 10.1080/08880018.2017.1396387. Epub 2017 Dec 4.
Gastrointestinal stromal tumors (GIST) are tumors of the gastrointestinal (GI) tract originating from the myenteric ganglion cells (interstitial cells of Cajal), that are very rare in children and adolescents. The most common clinical manifestation is acute or chronic, overt or occult GI bleeding although these tumors are asymptomatic in 10-30% of patients. We report a case of gastric GIST in a 11-year-old girl presenting with an iron deficiency refractory anemia without gastrointestinal symptoms and stool evidence of GI bleeding that caused a slight diagnostic delay.
胃肠道间质瘤（GIST）是起源于肌间神经节细胞（ Cajal间质细胞）的胃肠道肿瘤，在儿童和青少年中非常罕见。最常见的临床表现是急性或慢性、显性或隐性胃肠道出血，不过这些肿瘤在10%至30%的患者中是无症状的。我们报告一例11岁女孩的胃GIST病例，该女孩表现为缺铁性难治性贫血，无胃肠道症状，也没有胃肠道出血的粪便证据，这导致了轻微的诊断延迟。
