Khangura Taran, Uddin Gias, Davies Albert, Keating John
Department of Gastroenterology and Hepatology, Furness General Hospital, University Hospitals of Morecambe Bay NHS Foundation Trust, Barrow in Furness, Cumbria, LA14 4LF, United Kingdom.
Euroasian J Hepatogastroenterol. 2015 Jul-Dec;5(2):118-121. doi: 10.5005/jp-journals-10018-1149. Epub 2016 Jul 9.
Pancreatic sarcoidosis is one of the variant of systemic sarcoidosis which is extremely rare in literature and opined as an enigma. Hence, its diagnosis is very challenging as its presentation mimics pancreatic carcinoma. In view of a better understanding, we are presenting a case of pancreatic sarcoidosis to emphasize the above. To clearly distinguish sarcoidosis from malignancy, repeated computed tomography scans, Positron emission tomography scans, fine needle aspiration cytology, endoscopic retrograde cholangio-pancreatography supplemented with histology and relevant blood tests proved it to be a pancreatic sarcoidosis then a malignancy. Over the course, concrete evidence was divulged from lymph node biopsy and histology in clinching the diagnosis which later transformed into a malignancy. Therefore, we concluded it is a rare variant of pancreatic sarcoidosis and careful serial investigations include repeated imaging, histology and blood tests are essential to establish and most importantly differentiate the diagnosis.
Khangura T, Uddin G, Davies A, Keating J. A Rare Variant of Pancreatic Sarcoidosis: Diagnostic Challenge. Euroasian J Hepato-Gastroenterol 2015;5(2):118-121.
胰腺结节病是系统性结节病的一种变体,在文献中极为罕见,被视为一个谜团。因此,其诊断极具挑战性,因为其表现与胰腺癌相似。为了更好地理解,我们现呈现一例胰腺结节病病例以强调上述情况。为了明确区分结节病与恶性肿瘤,反复进行的计算机断层扫描、正电子发射断层扫描、细针穿刺细胞学检查、内镜逆行胰胆管造影并辅以组织学检查及相关血液检查,证实其为胰腺结节病而非恶性肿瘤。在此过程中,淋巴结活检和组织学检查为确诊提供了确凿证据,而后来该病例转变为恶性肿瘤。因此,我们得出结论,这是胰腺结节病的一种罕见变体,细致的系列检查,包括反复的影像学检查、组织学检查和血液检查,对于确立诊断以及最重要的鉴别诊断至关重要。
Khangura T, Uddin G, Davies A, Keating J. 胰腺结节病的一种罕见变体:诊断挑战。《欧亚肝脏胃肠病学杂志》2015年;5(2):118 - 121。