Studer U E, Ackermann D, Casanova G A, Zingg E J
Division of Urology, Inselspital, University of Berne, Switzerland.
Br J Urol. 1989 Jan;63(1):43-52. doi: 10.1111/j.1464-410x.1989.tb05122.x.
At the beginning of this century it was realised that peristalsis would cause incontinence if bowel was used for augmentation or substitution of the bladder. Trans-section of the antimesenteric border and cross-folding of the intestinal segments (Goodwin's cup-patch technique) is an efficient means of solving this problem and has been successfully used in the Kock pouch. We anastomosed the ileal low pressure reservoir to the membranous urethra in 22 male patients following radical cystoprostatectomy for bladder cancer. The mean observation time was 16 months (range 3-36). The capacity of the bladder substitute increased with time, the average being 450 ml after 6 months. In the first 4 patients with a short (2-5 cm) intestinal segment between the pouch and the urethra, micturition was prolonged, residual urine varied from 50 to 300 ml and bacteriuria was found. Occasional expulsions of several ml of urine were caused by peristalsis within this short tubular segment. In the following 18 patients, the low pressure reservoir was anastomosed directly to the membranous urethra. Micturition was good, with no notable residual urine, no bacteriuria and no paroxysmal urinary incontinence. However, a safety pad is used by half of the patients because once or twice a week, mainly at night, a few ml of urine may be lost. No significant changes in serum electrolytes, bicarbonate or creatinine were noted. With the three different antireflux techniques used, no obstructive or inflammatory changes in the upper urinary tracts were found, although no long-term antibiotic prophylaxis was given.
本世纪初人们认识到,如果用肠管来扩大或替代膀胱,蠕动会导致尿失禁。切开系膜对侧缘并对肠段进行交叉折叠(古德温杯状补片技术)是解决这一问题的有效方法,已成功应用于科克贮尿囊。我们对22例因膀胱癌行根治性膀胱前列腺切除术后的男性患者,将回肠低压贮尿囊与膜部尿道进行吻合。平均观察时间为16个月(范围3 - 36个月)。膀胱替代物的容量随时间增加,6个月后平均为450毫升。在前4例贮尿囊与尿道之间肠段较短(2 - 5厘米)的患者中,排尿时间延长,残余尿量在50至300毫升之间,且发现有菌尿。在这个短管状段内的蠕动偶尔会导致数毫升尿液排出。在随后的18例患者中,低压贮尿囊直接与膜部尿道吻合。排尿良好,无明显残余尿,无菌尿,也无阵发性尿失禁。然而,一半的患者使用了安全垫,因为每周会有一两次,主要是在夜间,会有几毫升尿液漏出。血清电解质、碳酸氢盐或肌酐未见明显变化。尽管未给予长期抗生素预防,但采用三种不同的抗反流技术时,上尿路未发现梗阻或炎症改变。