模仿足底纤维瘤病的足底筋膜上皮样肉瘤——临床和组织病理学误诊的严重陷阱

Epithelioid sarcoma of the plantar fascia mimicking Morbus Ledderhose - A severe pitfall for clinical and histopathological misinterpretation.

作者信息

Toepfer Andreas, Harrasser Norbert, Dreyer Florian, Mogler Carolin, Walther Markus, von Eisenhart-Rothe Rüdiger

机构信息

Schön Klinik München Harlaching, Zentrum für Fuß- und Sprunggelenkschirurgie, Harlachinger Str. 51, 81547 München, Germany; Klinik für Orthopädie und Sportorthopädie, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675 München, Germany; Wilhelm Sander-Therapieeinheitfür Knochen- und Weichteilsarkome am Klinikum rechts der Isar, Ismaninger Str. 22, 81675 München, Germany.

Klinik für Orthopädie und Sportorthopädie, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675 München, Germany; Wilhelm Sander-Therapieeinheitfür Knochen- und Weichteilsarkome am Klinikum rechts der Isar, Ismaninger Str. 22, 81675 München, Germany.

出版信息

Foot Ankle Surg. 2017 Dec;23(4):e25-e30. doi: 10.1016/j.fas.2017.03.013. Epub 2017 Apr 5.

DOI:10.1016/j.fas.2017.03.013

PMID:29202999

Abstract

Plantar fibromatosis, also known as Morbus Ledderhose, is a well known and frequently encountered disorder of the planta pedis. When conservative treatment fails, surgical therapy with complete resection is the therapeutical procedure of choice. Soft tissue sarcoma is a heterogeneous and rare malignant disease of the musculoskeletal system with over 50 histopathological subtypes which can potentially arise in any localization but is most commonly found at the extremities. Here, we report the case of an epithelioid sarcoma of the sole of the foot which was initially and repeatedly clinically and histopathologically misinterpreted as plantar fibromatosis, receiving insufficient resection and subsequently ending in amputation of the lower leg.

摘要

足底纤维瘤病，也称为莱德霍斯病，是一种广为人知且常见的足底疾病。当保守治疗失败时，完整切除的手术治疗是首选的治疗方法。软组织肉瘤是一种异质性且罕见的肌肉骨骼系统恶性疾病，有50多种组织病理学亚型，可能出现在任何部位，但最常见于四肢。在此，我们报告一例足底上皮样肉瘤病例，该病例最初在临床和组织病理学上被反复误诊为足底纤维瘤病，切除不充分，随后导致小腿截肢。