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人类大脑皮层组织的大规模梯度。

Large-Scale Gradients in Human Cortical Organization.

机构信息

Max Planck Research Group for Neuroanatomy & Connectivity, Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstrasse 1a, 04103 Leipzig, Germany; Neurocomputation and Neuroimaging Unit, Department of Education and Psychology, Free University of Berlin, 14195 Berlin, Germany.

Social Brain Lab, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA Amsterdam, Netherlands; Spinoza Centre for Neuroimaging, Meibergdreef 75, 1105 BK Amsterdam, Netherlands; Departments of Neurology and Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstrasse 1a, 04103 Leipzig, Germany.

出版信息

Trends Cogn Sci. 2018 Jan;22(1):21-31. doi: 10.1016/j.tics.2017.11.002. Epub 2017 Dec 1.

DOI:10.1016/j.tics.2017.11.002
PMID:29203085
Abstract

Recent advances in mapping cortical areas in the human brain provide a basis for investigating the significance of their spatial arrangement. Here we describe a dominant gradient in cortical features that spans between sensorimotor and transmodal areas. We propose that this gradient constitutes a core organizing axis of the human cerebral cortex, and describe an intrinsic coordinate system on its basis. Studying the cortex with respect to these intrinsic dimensions can inform our understanding of how the spectrum of cortical function emerges from structural constraints.

摘要

最近在绘制人类大脑皮质区域方面的进展为研究其空间排列的意义提供了基础。在这里,我们描述了跨越感觉运动和跨模态区域的皮质特征的主导梯度。我们提出,这个梯度构成了人类大脑皮层的一个核心组织轴,并在此基础上描述了一个内在坐标系。根据这些内在维度研究皮层可以帮助我们理解皮质功能的范围是如何从结构约束中产生的。

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