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昼夜不停的妊娠

Pregnancy Around the Clock.

机构信息

Department of Obstetrics and Fetal Medicine, Laboratory for Experimental Feto-Maternal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Department of Obstetrics and Fetal Medicine, Laboratory for Experimental Feto-Maternal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

Trends Mol Med. 2018 Jan;24(1):1-3. doi: 10.1016/j.molmed.2017.11.007. Epub 2017 Dec 5.

DOI:10.1016/j.molmed.2017.11.007
PMID:29203370
Abstract

A recent study introduced the existence of an 'immune clock' in pregnancy; during the course of gestation, peripheral blood cells from pregnant women were analyzed by mass cytometry using a single-cell signaling-based elastic net algorithm. The insights will undoubtedly promote the testing of such a clock - possibly in synergy with other pacemakers - to potentially predict pregnancy complications.

摘要

最近的一项研究介绍了妊娠中“免疫时钟”的存在;在妊娠过程中,使用基于单细胞信号的弹性网算法通过质谱细胞术分析孕妇的外周血细胞。这些见解无疑将促进对这种时钟的检测 - 可能与其他起搏器协同作用 - 以潜在地预测妊娠并发症。

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1
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引用本文的文献

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The role of FAS, FAS-L, BAX, and BCL-2 gene polymorphisms in determining susceptibility to unexplained recurrent pregnancy loss.FAS、FAS-L、BAX 和 BCL-2 基因多态性在不明原因复发性妊娠丢失易感性中的作用。
J Assist Reprod Genet. 2019 May;36(5):995-1002. doi: 10.1007/s10815-019-01441-w. Epub 2019 Apr 2.
2
Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy.人类妊娠期间免疫组学、转录组学、微生物组学、蛋白质组学和代谢组学适应性的多组学建模。
Bioinformatics. 2019 Jan 1;35(1):95-103. doi: 10.1093/bioinformatics/bty537.