Global Health Institute, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, P. R. China.
Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, P. R. China.
Sci Rep. 2017 Dec 4;7(1):16895. doi: 10.1038/s41598-017-16819-y.
In this study, we examined the associations of general and central obesity and hypertension among Chinese children. Data was collected from 1626 children aged 7-16 years and their parents in four mega-cities across China. Mixed effect models examined associations of general and central obesity with hypertension, and between body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), systolic blood pressure (SBP) and diastolic blood pressure (DBP). The prevalence of general obesity, central obesity, and hypertension among the children was 11.1%, 19.7%, and 9.0%, respectively. More boys had general and central obesity than girls (15.2% vs. 6.9%; 27.4% vs. 11.7%, respectively; both P < 0.0001). Sex difference in hypertension rate was not statistically significant (9.3% in boys vs. 8.8% in girls, P = 0.7341). Both SBP and DBP were positively associated with BMI, WC, and WHtR, regardless of sex and region. General obesity (OR = 5.94, 95% confidence interval [CI]: 3.69-9.55) and central obesity (OR = 3.45, 95% CI: 2.27-5.23) were strongly associated with hypertension. The prevalence of general obesity, central obesity, and hypertension was high among Chinese children in the four mega-cities across China. Children's BMI, WC, and WHtR were positively associated with their SBP and DBP. Obese children were 3-6 times more likely to have hypertension.
在这项研究中,我们研究了中国儿童的一般肥胖和中心性肥胖与高血压之间的关系。数据来自中国四个特大城市的 1626 名 7-16 岁的儿童及其家长。混合效应模型研究了一般肥胖和中心性肥胖与高血压之间的关系,以及体重指数(BMI)、腰围(WC)、腰高比(WHtR)、收缩压(SBP)和舒张压(DBP)之间的关系。研究对象中一般肥胖、中心性肥胖和高血压的患病率分别为 11.1%、19.7%和 9.0%。男孩的一般肥胖和中心性肥胖患病率高于女孩(15.2%比 6.9%;27.4%比 11.7%,均 P<0.0001)。男孩和女孩的高血压患病率之间没有统计学差异(男孩 9.3%,女孩 8.8%,P=0.7341)。SBP 和 DBP 均与 BMI、WC 和 WHtR 呈正相关,无论性别和地区如何。一般肥胖(OR=5.94,95%置信区间[CI]:3.69-9.55)和中心性肥胖(OR=3.45,95%CI:2.27-5.23)与高血压密切相关。中国四个特大城市的儿童中,一般肥胖、中心性肥胖和高血压的患病率较高。儿童的 BMI、WC 和 WHtR 与 SBP 和 DBP 呈正相关。肥胖儿童患高血压的可能性是正常儿童的 3-6 倍。