Patel Krupa R, Phillips David J, Leibowitz Jason M, Scognamiglio Theresa, Banuchi Victoria E, Kuhel William I, Kutler David I, Cohen Marc A
Weill Cornell Medical College, New York, NY 10065, USA.
Department of Otolaryngology-Head and Neck Surgery, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA.
World J Otorhinolaryngol Head Neck Surg. 2016 Jan 26;2(1):28-37. doi: 10.1016/j.wjorl.2016.01.001. eCollection 2016 Mar.
To assess the characteristics and quality of cost utility analyses (CUA) related to otolaryngology within the CEA registry and to summarize their collective results.
All cost-utility analyses published between 1976 and 2011 contained in the Cost-Effectiveness Analysis Registry (CEA Registry) were evaluated. Topics that fall within the care of an otolaryngologist were included in the review regardless of the presence of an otolaryngologist author. Potential associations between various study characteristics and CEA registry quality scores were evaluated using the Pearson product moment correlation coefficient.
Sixty-one of 2913 (2.1%) total CUA publications screened were related to otolaryngology. Eighteen of 61 (29.5%) publications included an otolaryngologist as an author. Fourteen studies agreed on the cost effectiveness of at least unilateral cochlear implantation and six of seven (85.7%) studies demonstrated the cost effectiveness of continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA). Forty-six percent (28 of 61) of all manuscripts were published between 2008 and 2011. A more recent publication year was associated with a higher CEA registry quality score while the presence of an otolaryngologist author and journal impact factor had no significant correlation with the quality of the CUA.
Based on current evidence in the CEA registry, unilateral cochlear implantation for hearing loss and CPAP for OSA are both cost-effective therapeutic interventions. Although CUAs in otolaryngology have increased in quantity and improved in quality in more recent years, there is a relative lack of CUAs in otolaryngology in comparison to other subspecialties.
评估成本效用分析（CUA）登记处中与耳鼻咽喉科相关的分析的特征和质量，并总结其总体结果。
对成本效益分析登记处（CEA登记处）中1976年至2011年间发表的所有成本效用分析进行评估。无论是否有耳鼻咽喉科作者，属于耳鼻咽喉科医生诊疗范围内的主题均纳入本综述。使用Pearson积差相关系数评估各种研究特征与CEA登记处质量评分之间的潜在关联。
在筛选的2913篇CUA出版物中，61篇（2.1%）与耳鼻咽喉科相关。61篇出版物中有18篇（29.5%）将耳鼻咽喉科医生列为作者。14项研究就至少单侧人工耳蜗植入的成本效益达成一致，7项研究中有6项（85.7%）表明持续气道正压通气（CPAP）治疗阻塞性睡眠呼吸暂停（OSA）具有成本效益。所有手稿中有46%（61篇中的28篇）在2008年至2011年间发表。较新的出版年份与较高的CEA登记处质量评分相关，而耳鼻咽喉科作者的存在和期刊影响因子与CUA的质量无显著相关性。
根据CEA登记处的现有证据，单侧人工耳蜗植入治疗听力损失和CPAP治疗OSA都是具有成本效益的治疗干预措施。尽管近年来耳鼻咽喉科的CUA数量有所增加且质量有所提高，但与其他亚专业相比，耳鼻咽喉科的CUA相对较少。
