静脉注射免疫球蛋白在川崎病治疗中的作用。
Role of intravenous immunoglobulin in the treatment of Kawasaki disease.
作者信息
Lo Mindy S, Newburger Jane W
机构信息
Division of Immunology, Boston Children's Hospital, Boston, MA.
Department of Pediatrics, Harvard Medical School, Boston, MA.
出版信息
Int J Rheum Dis. 2018 Jan;21(1):64-69. doi: 10.1111/1756-185X.13220. Epub 2017 Dec 5.
Intravenous immunoglobulin (IVIg) is a purified plasma product that is used for many immune-deficient conditions and autoimmune conditions. Use of IVIg for treatment for Kawasaki disease (KD) is critical for control of inflammation. The American Heart Association (AHA) recommends a single infusion of 2 g/kg preferably given during the first 10 days of illness. In this review, we have discussed the possible mechanisms of action of IVIg in KD and its clinical usage in this condition.
静脉注射免疫球蛋白（IVIg）是一种纯化的血浆制品，用于多种免疫缺陷疾病和自身免疫性疾病。使用IVIg治疗川崎病（KD）对于控制炎症至关重要。美国心脏协会（AHA）建议单次输注2 g/kg，最好在发病的前10天内给予。在本综述中，我们讨论了IVIg在KD中的可能作用机制及其在该疾病中的临床应用。
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