Hospital Sírio Libanês, São Paulo, Brazil; Division of Allergy, Department of Pulmonology, University Hospital of Montpellier, Montpellier, and Pierre Louis Institute of Epidemiology and Public Health, Sorbonne Universités, Paris, France.
Skin and Allergy Hospital, Helsinki University Central Hospital, FI-00029 Helsinki, Finland.
Respir Med. 2017 Sep;130:13-19. doi: 10.1016/j.rmed.2017.07.006. Epub 2017 Jul 11.
Asthma and allergic diseases can start in childhood and persist throughout life, but could also be manifested later, at any time for still misunderstood reasons. They are major chronic multifactorial respiratory diseases, for which prevention, early diagnosis and treatment is recognized as a priority for the Europe's public health policy and the United Nations. Given that allergy triggers (including infections, rapid urbanization leading to loss in biodiversity, pollution and climate changes) are not expected to change in a foreseeable future, it is imperative that steps are taken to develop, strengthen and optimize preventive and treatment strategies. Currently there are good treatments for asthma, several risk factors are known (e.g., allergies, rhinitis, tobacco smoke) and tools to control the disease have been developed. However, we are still uncertain how to prevent patients from developing asthma and allergic diseases. In this paper, we list the positive and negative experiences in this field as well as analyze the missing links in the process. This critical analysis will be the basis of setting-up an effective program for prevention and making, a process labeled as "implementation gaps".
哮喘和过敏性疾病可始于儿童期并持续终生,但也可能在以后的任何时候出现,其原因目前仍不甚清楚。它们是主要的慢性多因素呼吸道疾病,预防、早期诊断和治疗被认为是欧洲公共卫生政策和联合国的优先事项。鉴于过敏触发因素(包括感染、快速城市化导致生物多样性丧失、污染和气候变化)在可预见的未来预计不会改变,因此必须采取措施制定、加强和优化预防和治疗策略。目前,哮喘有很好的治疗方法,已知有几个风险因素(例如过敏、鼻炎、烟草烟雾),并且已经开发出了控制疾病的工具。然而,我们仍然不确定如何预防患者患上哮喘和过敏性疾病。在本文中,我们列出了该领域的正反两方面经验,并分析了该过程中的缺失环节。这一批判性分析将为制定有效的预防计划奠定基础,并被贴上“实施差距”的标签。