Campbell F C, Storey B E, Cullen P T, Cuschieri A
Dept. of Surgery, Ninewells Hospital and Medical School, Dundee.
Gut. 1989 Jan;30(1):39-45. doi: 10.1136/gut.30.1.39.
A computerised system for measurement of vibration at the abdominal surface was constructed which was addressed to the evaluation of gastrointestinal (GI) motor function. Preliminary studies revealed a dominant low frequency signal which was synchronous with the heartbeat and was considered representative of aortic pulsation. This was excluded by selective spectral filtration. The remaining signal was processed and measured by computer, with provision of quantitative energy values as well as of graphic display. The developed method, called surface vibration analysis (SVA) has been evaluated clinically; (a) against oral to caecal transit times (OCCT) of a standard solid meal, in five patients with severe postgastrectomy diarrhoea, seven patients with mild idiopathic diarrhoea and 22 healthy volunteers. (b) against prokinetic effects of a gastrointestinal stimulant (cisapride) in nine patients. In (a) postprandial SVA energy measurements were greater (SVA [*X (SEM)] = 406,933 (98,224] and oral to caecal transit of the solid meal was more rapid (OCTT = *90 (29) min) in the severe diarrhoea patients [postgastrectomy] than either the mild diarrhoea group (*SVA = 235,317 (50,780); *OCTT = *199 (42) min) or normal volunteers (*SVA = 212,062 (27,153); *OCTT = 242 (19) min) [p less than 0.01 for SVA and OCTT]. In the total group, an inverse correlation was observed between quantitative SVA energy values and oral to caecal transit times of solids (Spearman's rho = -0.486; p less than 0.01). In (b), drug stimulation of the GI tract caused an increase of fasting SVA measurements from *21,217 (5956) [before] to *41,937 (9606) [after] intravenous cisapride (p less than 0.05). This new technique may be useful for evaluation of gastrointestinal motor activity.
构建了一个用于测量腹部表面振动的计算机系统，旨在评估胃肠（GI）运动功能。初步研究发现了一个与心跳同步的占主导地位的低频信号，该信号被认为代表主动脉搏动。通过选择性频谱滤波将其排除。剩余信号由计算机进行处理和测量，提供定量能量值以及图形显示。所开发的方法称为表面振动分析（SVA），已在临床上进行了评估；（a）针对5例严重胃切除术后腹泻患者、7例轻度特发性腹泻患者和22名健康志愿者，与标准固体餐的口腔至盲肠转运时间（OCCT）进行对比。（b）针对9例患者中胃肠道刺激剂（西沙必利）的促动力作用进行对比。在（a）中，严重腹泻患者（胃切除术后）餐后SVA能量测量值更高（SVA [*X（SEM）]= 406,933（98,224）），固体餐的口腔至盲肠转运更快（OCTT = *90（29）分钟），高于轻度腹泻组（*SVA = 235,317（50,780）；*OCTT = *199（42）分钟）或正常志愿者（SVA = 212,062（27,153）；OCTT = 242（19）分钟）[SVA和OCTT的p值均小于0.01]。在整个组中，观察到定量SVA能量值与固体的口腔至盲肠转运时间之间呈负相关（斯皮尔曼等级相关系数rho = -0.486；p值小于0.01）。在（b）中，胃肠道的药物刺激使静脉注射西沙必利前的空腹SVA测量值从21,217（5956）增加到注射后的41,937（9606）（p值小于0.05）。这项新技术可能有助于评估胃肠运动活动。
