Harrison C R, Averette H E, Jarrell M A, Penalver M A, Donato D, Sevin B U
Department of Obstetrics and Gynecology, University of Miami School of Medicine, Florida 33124.
Gynecol Oncol. 1989 Mar;32(3):357-9. doi: 10.1016/0090-8258(89)90640-9.
From 1970 to 1986, 36 women were diagnosed to have primary fallopian tube cancer. Fifty-three percent of the patients were Stage III with a median adjusted survival of 27 months. Although varied adjunctive therapies were employed, none provided a clear survival benefit. Five "second-look" procedures were performed. Only one was negative, occurring in a Stage IIIC patient treated with combination chemotherapy. She has continued without evidence of disease 26 months following diagnosis. Recurrent disease was uniformly fatal, despite efforts at salvage therapy. Disease biology and response to therapy parallels that of similar stage epithelial carcinoma of the ovary.
1970年至1986年期间，36名女性被诊断患有原发性输卵管癌。53%的患者为Ⅲ期，中位调整生存期为27个月。尽管采用了多种辅助治疗方法，但均未带来明显的生存获益。进行了5次“二次探查”手术。只有1次结果为阴性，该患者为ⅡIC期，接受了联合化疗。诊断后26个月，她仍未出现疾病迹象。尽管采取了挽救治疗措施，但复发性疾病均导致死亡。疾病生物学特性及对治疗的反应与相似分期的卵巢上皮癌相似。
