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Am J Clin Dermatol. 2018 Jun;19(3):405-423. doi: 10.1007/s40257-017-0332-7.
Psoriasis is a chronic inflammatory skin condition affecting diverse racial/ethnic groups throughout the world. Large population-based studies suggest that psoriasis occurs most often in individuals of European ancestry, followed by black and Hispanic individuals, although the true prevalence of psoriasis in non-white individuals is likely underestimated. Despite similarities in psoriasis between ethnic groups, there are notable differences in the presentation, quality-of-life impact, and treatment of psoriasis with important implications for the management of non-white individuals. Overall, heterogeneity in psoriasis susceptibility alleles, in combination with cultural and socioeconomic factors, may explain these differences. In this article, we review the epidemiology, clinical presentation, genetic polymorphisms, quality-of-life impact, and treatment nuances of psoriasis in patients with skin of color.
银屑病是一种慢性炎症性皮肤疾病，影响着世界各地不同种族/民族的人群。基于人群的大型研究表明，银屑病最常发生在欧洲血统的个体中，其次是黑人和西班牙裔个体，尽管非白种人群中银屑病的真实患病率可能被低估了。尽管不同种族之间的银屑病存在相似之处，但在其表现、对生活质量的影响以及治疗方面存在显著差异，这对非白种人群的管理具有重要意义。总的来说，银屑病易感等位基因的异质性，加上文化和社会经济因素，可能解释了这些差异。在本文中，我们综述了有色人种患者银屑病的流行病学、临床表现、遗传多态性、对生活质量的影响以及治疗特点。
