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衣原体宫颈炎女性的阴道镜检查、活检及细胞学检查结果

Colposcopy, biopsy, and cytology results in women with chlamydial cervicitis.

作者信息

Dunlop E M, Garner A, Darougar S, Treharne J D, Woodland R M

机构信息

Diagnostic Clinics, Moorfields Eye Hospital, London.

出版信息

Genitourin Med. 1989 Jan;65(1):22-31. doi: 10.1136/sti.65.1.22.

DOI:10.1136/sti.65.1.22
PMID:2921049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1196182/
Abstract

Colposcopy and biopsy were carried out at diagnosis and at follow up of 222 women. Of 322 cervical biopsy specimens taken, 174 were from women with chlamydial cervicitis (patients) and 48 from control women (both at diagnosis) and 100 from 76 patients and seven controls at follow up. Of the 174 patients with chlamydial cervicitis, 158 (91%) had erythema compared with 9/48 (19%) controls, and 140 (81%) had "follicles" and lumps compared with three (6%) controls. The cervical polymorphonuclear leucocyte (PMNL) count in a high power (x 1000) field (HPF) was 85 in patients compared with 47/HPF in controls. Cervical ectopia was found in 154 (89%) patients compared with 32 (67%) controls. After treating the 174 patients, we found erythema in nine (5%) and "follicles" in 16 (9%); both conditions were disappearing. Lymphocytic germinal follicles were found on histology in only 5/165 patients compared with none in controls or in patients at follow up examination (after treatment for chlamydial cervicitis). Inclusions were found in 6/165 patients compared with none in controls or patients at follow up. Chlamydiae were found on electron microscopy in slides from seven out of 159 patients compared with none from controls or 81 subjects at follow up. Estimating numbers of inflammatory cells and measuring vascularity showed diffuse increases in lymphocytes and plasma cells and increases in vascularity in both endocervical and exocervical tissue of patients with chlamydial cervicitis. These increases were lessened by treatment.

摘要

对222名女性在诊断时及随访时进行了阴道镜检查和活检。在采集的322份宫颈活检标本中，174份来自衣原体宫颈炎女性（患者），48份来自对照女性（均在诊断时），100份来自76名患者和7名对照女性的随访标本。在174例衣原体宫颈炎患者中，158例（91%）有红斑，而对照女性为9/48例（19%）；140例（81%）有“滤泡”和肿块，对照女性为3例（6%）。衣原体宫颈炎患者高倍视野（×1000）下宫颈多形核白细胞（PMNL）计数为85，而对照女性为47/高倍视野。154例（89%）患者发现宫颈外翻，对照女性为32例（67%）。治疗174例患者后，发现9例（5%）有红斑，16例（9%）有“滤泡”；两种情况均在消失。组织学检查仅在165例患者中的5例发现淋巴细胞生发滤泡，对照女性及随访检查（衣原体宫颈炎治疗后）的患者均未发现。165例患者中的6例发现包涵体，对照女性及随访患者均未发现。电子显微镜检查发现159例患者中的7例玻片上有衣原体，对照女性及81名随访对象均未发现。炎症细胞计数和血管测量显示，衣原体宫颈炎患者宫颈内和宫颈外组织中的淋巴细胞和浆细胞弥漫性增加，血管增多。治疗后这些增加有所减轻。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf5/1196182/eaf50545f73a/genitmed00049-0032-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf5/1196182/21930c118bcb/genitmed00049-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf5/1196182/9d5e010939f0/genitmed00049-0033-b.jpg
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GENITAL INFECTION IN ASSOCIATION WITH TRIC VIRUS INFECTION OF THE EYE. III. CLINICAL AND OTHER FINDINGS. PRELIMINARY REPORT.生殖器感染与眼部三病毒感染相关。III. 临床及其他发现。初步报告。
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