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抗内皮糖蛋白单克隆抗体和贝伐单抗治疗难治性绒癌的女性患者获得持久缓解：来自新英格兰滋养细胞疾病中心、布莱根妇女医院和达纳-法伯癌症研究所的病例报告。

Durable remission for a woman with refractory choriocarcinoma treated with anti-endoglin monoclonal antibody and bevacizumab: A case from the New England Trophoblastic Disease Center, Brigham and Women's Hospital and Dana-Farber Cancer Institute.

机构信息

Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Dana-Farber Cancer Institute, Boston, MA, United States; New England Trophoblastic Disease Center, Boston, MA, United States.

Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Dana-Farber Cancer Institute, Boston, MA, United States; New England Trophoblastic Disease Center, Boston, MA, United States.

出版信息

Gynecol Oncol. 2018 Jan;148(1):5-11. doi: 10.1016/j.ygyno.2017.11.029. Epub 2017 Dec 6.

DOI:10.1016/j.ygyno.2017.11.029
PMID:29217138
Abstract

A 36-year-old with metastatic and refractory choriocarcinoma following single- and multi-agent chemotherapy and surgical metastectomy experienced a durable remission after receiving therapy with an anti-endoglin monoclonal antibody and bevacizumab. Treatment options and scientific advances in this disease are highlighted.

摘要

一名 36 岁患者在接受单一和多种药物化疗以及手术转移瘤切除术治疗后，发生转移性和耐药性绒癌，在接受抗内皮糖蛋白单克隆抗体和贝伐珠单抗治疗后获得持久缓解。本文重点介绍了该疾病的治疗选择和科学进展。

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