儿科重症监护病房护理后的神经学转归
Neurologic Outcomes Following Care in the Pediatric Intensive Care Unit.
作者信息
Caprarola Sherrill D, Kudchadkar Sapna R, Bembea Melania M
机构信息
Department of Pediatrics, Division of Pediatric Cardiology, Baylor College of Medicine/Texas Children's Hospital, 6621 Fannin St, Houston, TX, United States, 77030.
Departments of Anesthesiology and Critical Care Medicine, and Pediatrics, Johns Hopkins University School of Medicine, 1800 Orleans Street, Baltimore, MD, United States, 21287.
出版信息
Curr Treat Options Pediatr. 2017 Sep;3(3):193-207. doi: 10.1007/s40746-017-0092-x. Epub 2017 Jul 26.
PURPOSE OF REVIEW
With increasing survival of children requiring admission to pediatric intensive care units (PICU), neurodevelopmental outcomes of these patients are an area of increased attention. Our goal was to systematically review recently published literature on neurologic outcomes of PICU patients.
RECENT FINDINGS
Decline in neurofunctional status occurs in 3%-20% of children requiring PICU care. This proportion varies based on primary diagnosis and severity of illness, with children admitted for primary neurologic diagnosis, children who suffer cardiac arrest or who require invasive interventions during the PICU admission, having worse outcomes. Recent research focuses on early identification and treatment of modifiable risk factors for unfavorable outcomes, and on long-term follow-up that moves beyond global cognitive outcomes and is increasingly including tests assessing multidimensional aspects of neurodevelopment.
SUMMARY
The pediatric critical care research community has shifted focus from survival to survival with favorable neurologic outcomes of children admitted to the PICU.
综述目的
随着需要入住儿科重症监护病房（PICU）的儿童生存率不断提高，这些患者的神经发育结局成为了一个备受关注的领域。我们的目标是系统回顾最近发表的关于PICU患者神经学结局的文献。
最新发现
在需要PICU护理的儿童中，3%-20%会出现神经功能状态下降。这一比例因主要诊断和疾病严重程度而异，因原发性神经诊断入院的儿童、心脏骤停的儿童或在PICU住院期间需要进行侵入性干预的儿童，结局更差。近期研究集中于早期识别和治疗不良结局的可改变风险因素，以及长期随访，这种随访不再局限于整体认知结局，越来越多地纳入评估神经发育多维度方面的测试。
总结
儿科重症监护研究领域已将重点从生存转移到让入住PICU的儿童获得良好神经学结局的生存。
Zotero 插件