Ma Jun, He Yunfei, Wang An, Wang Weiheng, Xi Yanhai, Yu Jiangming, Ye Xiaojian
Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai, PR China.
Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai, PR China; Department of Spinal Surgery, Lanzhou General Hospital of Lanzhou Military Command Region, Lanzhou, PR China.
World Neurosurg. 2018 Feb;110:e1017-e1024. doi: 10.1016/j.wneu.2017.11.154. Epub 2017 Dec 7.
To identify the risk factors for foot drop in patients with lumbar disc herniation (LDH).
Two hundred thirty-six patients who underwent surgery for LDH were retrospectively reviewed. Foot drop was defined as tibialis anterior muscle strength of lower than grade 4 by the manual muscle test. Possible risk factors, including demographic and radiographic parameters, were evaluated by multivariate logistic regression analysis.
Fifty-two patients (22.9%) suffered from foot drop. Multivariate logistic regression analysis revealed that diabetes mellitus, disc calcification, patients who had an acute episode or acute-on-chronic episode, and patients who presented with lateral recess or extraforaminal type of disc herniation were at greater risk of foot drop. Notably, patients who had a canal occupancy rate of more than 50% were at greater risk of foot drop compared with patients who had a canal occupy rate of less than 25%. With a 1.0-mm increase in anteroposterior diameter of the index spinal canal, the risk of developing foot drop decreased to 51.8% in these patients (P < 0.05).
The following factors may affect the development of foot drop in patients with LDH: 1) diabetes mellitus; 2) patients with an acute episode or acute-on-chronic episode; 3) patients with lateral recess or foraminal type of herniation; 4) disc calcification; 5) canal occupancy rate greater than 50%; and 6) the anteroposterior diameter of canal. Surgical treatments for patients with those risk factors should be implemented positively during the follow-up period to reduce possible adverse outcomes.
确定腰椎间盘突出症(LDH)患者足下垂的危险因素。
回顾性分析236例行LDH手术的患者。足下垂定义为通过徒手肌力测试胫前肌肌力低于4级。通过多因素逻辑回归分析评估包括人口统计学和影像学参数在内的可能危险因素。
52例患者(22.9%)发生足下垂。多因素逻辑回归分析显示,糖尿病、椎间盘钙化、有急性发作或慢性急性发作的患者以及表现为侧隐窝或椎间孔外型椎间盘突出的患者发生足下垂的风险更高。值得注意的是,椎管占位率超过50%的患者与椎管占位率低于25%的患者相比,发生足下垂的风险更高。在这些患者中,随着索引椎管前后径每增加1.0 mm,发生足下垂的风险降至51.8%(P<0.05)。
以下因素可能影响LDH患者足下垂的发生:1)糖尿病;2)有急性发作或慢性急性发作的患者;3)侧隐窝或椎间孔型突出的患者;4)椎间盘钙化;5)椎管占位率大于50%;6)椎管前后径。对于有这些危险因素的患者,应在随访期间积极实施手术治疗,以减少可能的不良后果。