Sacks Gregory I, Destefano Vincent, Fiore Susan M, Davis Raphael P, Ahknoukh Samuel, Mushlin Harry M
Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.
Department of Neurosurgery, Stony Brook University Hospital, Stony Brook, NY, USA.
Int J Spine Surg. 2024 Sep 20;18(6):637-44. doi: 10.14444/8650.
Lumbar disc herniation (LDH) is a common cause of radicular pain with an annual incidence between 5 and 20 cases per 1000 adults. LDH is typically treated by microdiscectomy, of which more than 300,000 are performed in the United States each year. Despite this frequency, 25% to 33% of patients report poor surgical outcomes. This study sought to present a retrospective analysis of patients who underwent microdiscectomy surgery for the treatment of LDH with the aim of identifying demographic, historical, and surgical factors that may contribute to inadequate surgical results.
A retrospective study of 241 patients at Stony Brook Medicine from 2017 to 2022 was performed, 123 of whom had follow-up of 90 days or more and were included for final analysis. Data collection included demographics, medical/surgical history, and surgical methodology. Good outcomes were defined as meeting the absolute point change threshold (ACT)-3.5pt reduction in pain reported by the Numerical Rating System (NRS) or the resolution of either radicular pain or neurological symptoms.
Univariate analysis revealed that 100% of patients with prior fusion surgery ( = 0.039) and 73.2% who underwent preoperative physical therapy (PT; = 0.032) failed to meet the ACT. Additionally, 79.1% ( = 0.021) and 82.8% ( = 0.026) of patients who had PT had residual radicular pain and neurological symptoms, respectively. Multivariate logistic regression confirmed correlations between preoperative PT and failure to meet the ACT ( = 0.030, OR = 0.252) and resolution of radicular ( = 0.006, OR = 0.196) and neurological ( = 0.030, OR = 0.177) complaints. ACT directly correlated with higher preoperative NRS scores in univariate ( = 0.0002) and multivariate ( = 0.002, OR = 1.554) analyses.
Our results show that higher preoperative NRS scores, PT, and prior fusion surgery are associated with poorer outcomes. While PT is considered a viable nonoperative treatment for LDH, our findings suggest detrimental effects when preceding surgery, indicating the need for additional research into the effects of PT on patients with high grade LDH.
腰椎间盘突出症(LDH)是导致神经根性疼痛的常见原因,每年每1000名成年人中的发病率为5至20例。LDH通常通过显微椎间盘切除术进行治疗,在美国每年有超过30万例此类手术。尽管手术频率如此之高,但仍有25%至33%的患者报告手术效果不佳。本研究旨在对接受显微椎间盘切除术治疗LDH的患者进行回顾性分析,以确定可能导致手术效果不佳的人口统计学、病史和手术因素。
对2017年至2022年在石溪医学中心的241例患者进行回顾性研究,其中123例患者的随访时间为90天或更长时间,并纳入最终分析。数据收集包括人口统计学、医疗/手术史和手术方法。良好的结果定义为达到绝对点变化阈值(ACT)——数字评分系统(NRS)报告的疼痛减轻3.5分,或神经根性疼痛或神经症状得到缓解。
单因素分析显示,既往有融合手术史的患者中有100%(P = 0.039)以及接受术前物理治疗(PT)的患者中有73.2%(P = 0.032)未达到ACT。此外,接受PT治疗的患者中分别有79.1%(P = 0.021)和82.8%(P = 0.026)存在残留的神经根性疼痛和神经症状。多因素逻辑回归证实术前PT与未达到ACT(P = 0.030,OR = 0.252)以及神经根性(P = 0.006,OR = 0.196)和神经症状(P = 0.030,OR = 0.177)的缓解之间存在相关性。在单因素(P = 0.0002)和多因素(P = 0.002,OR = 1.554)分析中,ACT与术前较高的NRS评分直接相关。
我们的结果表明,术前较高的NRS评分、PT和既往融合手术史与较差的手术效果相关。虽然PT被认为是LDH一种可行 的非手术治疗方法,但我们的研究结果表明术前进行PT会产生不利影响,这表明需要对PT对重度LDH患者的影响进行更多研究。