Department of Clinical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UK.
Department of Clinical Oncology, Cancer Centre, Belfast City Hospital, Belfast, UK; Centre for Cancer Research and Cell Biology, Queen's University of Belfast, Belfast, UK.
Clin Oncol (R Coll Radiol). 2018 Feb;30(2):101-109. doi: 10.1016/j.clon.2017.11.003. Epub 2017 Dec 6.
In spite of recent improvements in both the technical delivery of radiotherapy and systemic therapy in the treatment of non-small cell lung cancer, local recurrence rates after radiotherapy remain a significant challenge. In the setting of local relapse after radiotherapy, treatments such as surgical resection or radiofrequency ablation are often not appropriate owing to disease and patient factors. Re-irradiation may be a potential treatment option. This overview considers the published evidence and potential treatment strategies.
尽管近年来在非小细胞肺癌的放射治疗和系统治疗的技术提供方面都有所改进，但放射治疗后的局部复发率仍然是一个重大挑战。在放射治疗后局部复发的情况下，由于疾病和患者因素，手术切除或射频消融等治疗方法往往不适用。再放疗可能是一种潜在的治疗选择。本综述考虑了已发表的证据和潜在的治疗策略。
