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一名囊性纤维化患者发生严重的哌拉西林-他唑巴坦诱导的溶血。

Severe piperacillin-tazobactam-induced hemolysis in a cystic fibrosis patient.

作者信息

Kerkhoff Andrew D, Patrick Lauren, Cornett Patricia, Kleinhenz Mary-Ellen, Brondfield Sam

机构信息

Department of Medicine University of California San Francisco School of Medicine San Francisco California.

Department of Neurology University of California San Francisco School of Medicine San Francisco California.

出版信息

Clin Case Rep. 2017 Nov 2;5(12):2059-2061. doi: 10.1002/ccr3.1256. eCollection 2017 Dec.

Abstract

Piperacillin-tazobactam is one of the most common causes of drug-induced immune hemolytic anemia (DIIHA) and is frequently utilized, especially in patients with cystic fibrosis (CF). Here, we report a case of life-threatening piperacillin-tazobactam-associated DIIHA in a 30-year-old woman with CF and propose management recommendations for piperacillin-tazobactam-associated DIIHA in CF patients.

摘要

哌拉西林-他唑巴坦是药物性免疫性溶血性贫血(DIIHA)最常见的病因之一,且经常被使用,尤其是在囊性纤维化(CF)患者中。在此,我们报告一例30岁患有CF的女性发生危及生命的哌拉西林-他唑巴坦相关性DIIHA的病例,并提出CF患者中哌拉西林-他唑巴坦相关性DIIHA的管理建议。

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引用本文的文献

本文引用的文献

1
Piperacillin-induced mild haemolytic anaemia in a 44-year-old patient with cystic fibrosis.
BMJ Case Rep. 2016 Oct 24;2016:bcr2016216937. doi: 10.1136/bcr-2016-216937.
2
Pulmonary Exacerbations in Children with Cystic Fibrosis.
Ann Am Thorac Soc. 2015 Nov;12 Suppl 2:S200-6. doi: 10.1513/AnnalsATS.201502-098AW.
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Blood Rev. 2010 Jul-Sep;24(4-5):143-50. doi: 10.1016/j.blre.2010.06.004. Epub 2010 Jul 21.
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Piperacillin-induced immune hemolytic anemia in an adult with cystic fibrosis.
Case Rep Med. 2010;2010:161454. doi: 10.1155/2010/161454. Epub 2010 Jun 2.
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Piperacillin-induced immune hemolysis: new cases and a concise review of the literature.
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