Pryds O A, Petersen S A, Jacobsen J R, Gjerris F
Ugeskr Laeger. 1989 Feb 27;151(9):570-2.
Four infants treated with ventriculo-atrial shunt for hydrocephalus developed sudden pulmonary hypertension, several years after the first operation. All infants died in spite of replacement of the distal shunt and AK treatment. At necropsy, old microemboli were found in the small lung vessels in two infants whereas the two other infants were suspected of having the same lesions from clinical investigations. The overall frequency for this complication was estimated to be 6.7% (95% CI 1.4-14.3%).
4例因脑积水接受脑室-心房分流术治疗的婴儿在首次手术后数年出现突发性肺动脉高压。尽管更换了分流管远端并进行了抗凝血治疗，但所有婴儿均死亡。尸检时，在2例婴儿的肺小血管中发现了陈旧性微栓子，而另外2例婴儿根据临床检查怀疑有相同病变。据估计，这种并发症的总体发生率为6.7%（95%置信区间1.4 - 14.3%）。
