阴茎原发性未分化多形性肉瘤
Primary Undifferentiated Pleomorphic Sarcoma of the Penis.
作者信息
Yoo Hyung Sun, Satti Suma, Matrana Marc
机构信息
The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA.
Department of Hematology and Oncology, Ochsner Clinic Foundation, New Orleans, LA.
出版信息
Ochsner J. 2017 Winter;17(4):434-437.
BACKGROUND
Primary penile sarcoma is a rare disease that affects men of all ages. Different subtypes of primary penile sarcoma exist, with the rarest being pleomorphic sarcoma. Delays in presentation and diagnosis of primary penile sarcoma have been reported because of its benign-appearing presenting features and rarity. If penile sarcoma is left untreated, the clinical consequence is metastasis that is fatal in most cases.
CASE REPORT
We report an extremely rare case of undifferentiated pleomorphic sarcoma of the penis in a 59-year-old patient who initially presented with a slow-growing penile nodule. The tumor was surgically excised, but the patient experienced local recurrence and, despite receiving chemotherapy and surgery, died of metastatic disease 15 months after initial presentation.
CONCLUSION
Vigilance regarding biopsy and intervention for penile nodules may lead to early diagnosis and improved clinical outcomes.
背景
原发性阴茎肉瘤是一种罕见疾病，可累及所有年龄段男性。原发性阴茎肉瘤存在不同亚型，其中最罕见的是多形性肉瘤。由于原发性阴茎肉瘤的表现特征看似良性且罕见，已有报道称其在就诊和诊断方面存在延迟。如果阴茎肉瘤不进行治疗，临床后果是转移，在大多数情况下会致命。
病例报告
我们报告了一例极为罕见的59岁男性阴茎未分化多形性肉瘤病例，该患者最初表现为阴茎缓慢生长的结节。肿瘤通过手术切除，但患者出现局部复发，尽管接受了化疗和手术，在初次就诊15个月后死于转移性疾病。
结论
对阴茎结节进行活检和干预时保持警惕可能会实现早期诊断并改善临床结局。
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