Schilling R F, Crowley J J
Am J Hematol. 1979;7(1):1-10. doi: 10.1002/ajh.2830070102.
In a retrospective search for prognostic factors in 127 patients with chronic myelocytic leukemia we found that thrombocytopenic patients had a significantly shortened life-span. Patients with the Philadelphia chromosome lived longer and were significantly younger than those lacking it. Females lived longer than males. Numerous other single features failed to correlate significantly with survival, but several combinations of two did. Patients having a low hematocrit with a low white blood count had an impressively short life-span compared to all others. Those having a high cholesterol and a low uric acid survived significantly longer than all others.
在对127例慢性粒细胞白血病患者进行的回顾性预后因素研究中，我们发现血小板减少的患者寿命显著缩短。有费城染色体的患者比没有该染色体的患者寿命更长且明显更年轻。女性比男性寿命长。许多其他单一特征与生存率无显著相关性，但有几种两个特征的组合与生存率相关。与其他所有患者相比，血细胞比容低且白细胞计数低的患者寿命极短。胆固醇高且尿酸低的患者比其他所有患者的生存时间显著更长。
