Centre for NMR and Structural Chemistry, CSIR-Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad, 500 007, India.
UM-DAE-Centre for Excellence in Basic Sciences, University of Mumbai, Kalina Campus, Santa Cruz, Mumbai, 400 098, India.
Magn Reson Chem. 2018 Oct;56(10):963-968. doi: 10.1002/mrc.4693. Epub 2018 Jan 8.
The present manuscript reports development and applications of real-time homonuclear broadband decoupled pure shift version of in-phase zero-quantum filtered COSY (PS-IPZF-COSY) and clean in-phase COSY (PS-CLIP-COSY) pulse schemes. In contrast to the conventional COSY schemes, these pure shift versions provide enhanced spectral resolution and simplify the chemical shift correlation analysis of scalar coupled spins in complex organic molecules, which are exemplified for erythromycin A, estradiol, and a mixture of estradiol and testosterone.
本文报道了实时同核宽带去耦纯相零量子滤波相关谱（PS-IPZF-COSY）和清洁同相相关谱（PS-CLIP-COSY）脉冲方案的开发及应用。与传统的 COSY 方案相比，这些纯相版本提供了更高的光谱分辨率，并简化了复杂有机分子中标量耦合自旋的化学位移相关分析，文中以红霉素 A、雌二醇和雌二醇与睾酮混合物为例进行了说明。
