Tong F, Liang Y, Shi Q, Zhang L, L W H, Zhou Y W
Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Fa Yi Xue Za Zhi. 2017 Feb;33(1):48-51. doi: 10.3969/j.issn.1004-5619.2017.01.012. Epub 2017 Feb 25.
Insulin as a common clinical hypoglycemic agent can effectively control serves to lower the concentration of blood glucose. However, insulin overdose can lead to death. In the whole fatal cases of insulin overdose, medical accident is the most common, followed by suicide. Though insulin homicide is extremely rare, it deserves great attention. Though there are some researches about insulin poisoning on forensic toxicology and pathology, it is still a difficult task in forensic practice. In this paper, the mechanism of death, pathological changes, detection methods and diagnose criteria of insulin overdose will be discussed in the view of forensic toxicology and pathology. We hope that this paper could enhance relative knowledges of insulin poisoning for medical examiners.
胰岛素作为一种常见的临床降糖药物,能够有效控制血糖水平,降低血糖浓度。然而,胰岛素过量会导致死亡。在胰岛素过量致死的所有案例中,医疗事故最为常见,其次是自杀。尽管胰岛素杀人极为罕见,但仍值得高度关注。虽然在法医毒理学和病理学方面已有一些关于胰岛素中毒的研究,但在法医实践中它仍是一项艰巨的任务。本文将从法医毒理学和病理学的角度探讨胰岛素过量的死亡机制、病理变化、检测方法及诊断标准。我们希望本文能够增进法医对胰岛素中毒相关知识的了解。