Smith D J, Busuito M J, Velanovich V, Spotts J, Heggers J P, Robson M C
Division of Plastic and Reconstructive Surgery, Wayne State University School of Medicine, Detroit, MI.
Ann Plast Surg. 1989 Jan;22(1):19-24. doi: 10.1097/00000637-198901000-00004.
The increasing incidence of illicit intravenous drug abuse has reached epidemic proportions in western society. Although the accompanying infectious complications such as hepatitis and acquired immunodeficiency syndrome receive the most notoriety, injection injuries are causing an increasing number of problems. A retrospective review of patients requiring admission for acute or chronic drug injection injuries of the upper extremities was made at the Detroit Receiving Hospital from 1980 through 1985. The demographical, historical, physical, microbiological, and follow-up data were analyzed. The majority of the injuries involved subcutaneous injections into the hand with accompanying inflammatory or infectious complications. The bacteriological data revealed unique characteristics and did not reflect patterns expected from inoculation of normal skin flora. A treatment regimen based on the data is proposed.
非法静脉注射药物滥用现象在西方社会日益普遍，已呈泛滥之势。尽管诸如肝炎和获得性免疫缺陷综合征等伴随的感染性并发症最为声名狼藉，但注射损伤引发的问题也越来越多。1980年至1985年期间，底特律接收医院对因上肢急性或慢性药物注射损伤而需住院治疗的患者进行了回顾性研究。分析了人口统计学、病史、体格检查、微生物学及随访数据。大多数损伤为手部皮下注射，并伴有炎症或感染并发症。细菌学数据显示出独特的特征，并未反映出正常皮肤菌群接种所预期的模式。基于这些数据提出了一种治疗方案。
