出生时对酸中毒足月儿进行脐带挤血：新生儿结局
Umbilical cord milking at birth for term newborns with acidosis: neonatal outcomes.
作者信息
Katheria Anup, Mercer Judith, Brown Melissa, Rich Wade, Baker Katie, Harbert M J, Pierce Brianna, Hassen Kasim, Finer Neil
机构信息
Neonatal Research Institute at Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA, USA.
University of Rhode Island, Kingston, RI, USA.
出版信息
J Perinatol. 2018 Mar;38(3):240-244. doi: 10.1038/s41372-017-0011-9. Epub 2017 Dec 12.
OBJECTIVE
To determine if umbilical cord milking is detrimental in compromised term/near-term infants.
STUDY DESIGN
A retrospective analysis of infants with abnormal cord gases (cord arterial or venous pH of ≤ 7.1 or base deficit > -12). We collected maternal risk factors, cord management, birth, and neonatal outcomes during hospitalization.
RESULT
We found 157 infants who met the criteria for abnormal cord gases. Thirty-six of those had umbilical cord milking at delivery. There was no significant difference in neonatal outcomes, but fewer infants in the cord milking group needed resuscitation (38 vs. 56%, p = 0.07) and ongoing respiratory support (19 vs. 31%, p = 0.16) compared to the immediate clamping group.
CONCLUSIONS
While not significant, infants who received cord milking at birth needed less resuscitation and ongoing respiratory support. This study suggests that umbilical cord milking appears to be a safe therapy when acidosis is present and when resuscitation is needed.
目的
确定脐带挤奶对足月儿/近足月儿是否有害。
研究设计
对脐带血气异常（脐动脉或静脉pH值≤7.1或碱缺失＞-12）的婴儿进行回顾性分析。我们收集了母亲的危险因素、脐带处理、分娩及住院期间的新生儿结局。
结果
我们发现157名婴儿符合脐带血气异常标准。其中36名在分娩时进行了脐带挤奶。与立即钳夹组相比，新生儿结局无显著差异，但脐带挤奶组需要复苏的婴儿较少（38%对56%，p = 0.07），且持续呼吸支持的婴儿也较少（19%对31%，p = 0.16）。
结论
虽然差异不显著，但出生时接受脐带挤奶的婴儿需要的复苏和持续呼吸支持较少。这项研究表明，当存在酸中毒且需要复苏时，脐带挤奶似乎是一种安全的治疗方法。
Zotero 插件