Duvic M, Lowe L, Rapini R P, Rodriguez S, Levy M L
Department of Dermatology, University of Texas Health Science Center, Houston.
Arch Dermatol. 1989 Mar;125(3):397-401.
The cutaneous manifestations of the acquired immunodeficiency syndrome include infections and neoplasms resulting from the immunodeficient state. Seven patients presenting with the symptom of new eruptive nevi with dysplastic histologic findings are described. These patients noted multiple new moles, which occurred in crops and in individuals without the dysplastic nevus syndrome (familial melanomas). This symptom occurred as the patients became symptomatic from their human immunodeficiency virus infection, developing acquired immunodeficiency syndrome or its related complex. Further confirmation and study of this phenomenon could lead to a better understanding of the pathogenesis of melanocytic dysplasia and its relationship to the immune system.
获得性免疫缺陷综合征的皮肤表现包括免疫缺陷状态导致的感染和肿瘤。本文描述了7例出现新发痣且组织学表现为发育异常的患者。这些患者发现有多个新痣，呈分批出现，且患者无发育异常痣综合征（家族性黑色素瘤）。随着患者因人类免疫缺陷病毒感染出现症状、发展为获得性免疫缺陷综合征或其相关综合征，这一症状随之出现。对这一现象的进一步证实和研究可能有助于更好地理解黑素细胞发育异常的发病机制及其与免疫系统的关系。
