a Epidemic Intelligence Service, Centers for Disease Control and Prevention , Atlanta , GA , USA.
b Office of Noncommunicable Diseases, Injury, and Environmental Health , National Center for Environmental Health, Division of Environmental Hazards and Health Effects, Health Studies Branch, Centers for Disease Control and Prevention , Atlanta , GA , USA.
Clin Toxicol (Phila). 2018 Jul;56(7):646-652. doi: 10.1080/15563650.2017.1413194. Epub 2017 Dec 13.
The National Poison Data System (NPDS) is a database and surveillance system for US poison centers (PCs) call data. The Centers for Disease Control and Prevention (CDC) and American Association of Poison Control Centers (AAPCC) use NPDS to identify incidents of potential public health significance. State health departments are notified by CDC of incidents identified by NPDS to be of potential public health significance. Our objective was to describe the public health impact of CDC's notifications and the use of NPDS data for surveillance.
We described how NPDS data informed three public health responses: the Deepwater Horizon incident, national exposures to laundry detergent pods, and national exposures to e-cigarettes. Additionally, we extracted survey results of state epidemiologists regarding NPDS incident notification follow-up from 1 January 2015 to 31 December 2016 to assess current public health application of NPDS data using Epi Info 7.2 and analyzed data using SAS 9.3. We assessed whether state health departments were aware of incidents before notification, what actions were taken, and whether CDC notifications contributed to actions.
NPDS data provided evidence for industry changes to improve laundry detergent pod containers safety and highlighted the need to regulate e-cigarette sale and manufacturing. NPDS data were used to improve situational awareness during the 2010 Deepwater Horizon oil spill. Of 59 health departments and PCs who responded to CDC notifications about anomalies (response rate = 49.2%), 27 (46%) reported no previous awareness of the incident, and 20 (34%) said that notifications contributed to public health action.
Monitoring NPDS data for anomalies can identify emerging public health threats and provide evidence-based science to support public health action and policy changes.
国家毒物数据系统(NPDS)是一个美国毒物中心(PC)呼叫数据的数据库和监测系统。疾病控制与预防中心(CDC)和美国毒物控制中心协会(AAPCC)使用 NPDS 来识别潜在公共卫生意义的事件。CDC 会通知州卫生部门注意 NPDS 识别出的潜在公共卫生意义的事件。我们的目的是描述 CDC 通知的公共卫生影响以及使用 NPDS 数据进行监测。
我们描述了 NPDS 数据如何为三种公共卫生应对措施提供信息:深水地平线事件、全国范围内的洗衣液包装暴露事件和全国范围内的电子烟暴露事件。此外,我们还从 2015 年 1 月 1 日至 2016 年 12 月 31 日提取了关于 NPDS 事件通知后续情况的州流行病学家调查结果,以评估当前使用 Epi Info 7.2 对 NPDS 数据的公共卫生应用,并使用 SAS 9.3 分析数据。我们评估了州卫生部门在通知前是否了解事件、采取了哪些行动以及 CDC 通知是否有助于采取行动。
NPDS 数据为改善洗衣液包装安全提供了行业变革的证据,并强调需要规范电子烟的销售和制造。NPDS 数据用于提高 2010 年深水地平线石油泄漏期间的情况意识。在对关于异常的 CDC 通知做出回应的 59 个卫生部门和 PC 中(响应率为 49.2%),27 个(46%)表示以前不了解该事件,20 个(34%)表示通知有助于公共卫生行动。
监测 NPDS 数据中的异常情况可以识别新出现的公共卫生威胁,并提供基于证据的科学依据,以支持公共卫生行动和政策变化。