Psychiatric Research Centre, Mental Health Center Copenhagen,Copenhagen,Capital Region of Denmark.
iPsych - The Lundbeck Foundation Initiative for Integrative Psychiatric Research,Denmark.
Psychol Med. 2018 Sep;48(12):1993-2000. doi: 10.1017/S0033291717003518. Epub 2017 Dec 14.
Schizophrenia (SZ) and bipolar disorder (BP) are causes of severe disability worldwide and parents' severe mental illness (SMI) is associated with childhood adversity, and socio-emotional and cognitive problems in children. Yet, how parental BP and SZ affect educational attainment in offspring is still unclear.
We included all children (N = 684.248) born and living in Denmark between 1986 and 1996 and their parents. Our follow-up lasted from 1986 until children's graduation in 2014. The main outcome variable was their school grades following their primary education. School outcomes were divided into four categories: not graduated, low-grade point average (GPA), medium GPA and high GPA. We then performed a multiple logistic regression with medium GPA as the reference category, with the children of parents without SZ or BP as the reference group.
Children of parents with SZ faced higher odds than their peers of not graduating primary education (OR 2.6), along with low GPA (odds ratios (OR) 1.6) and lower odds for a high GPA (OR 0.7). Moreover, it was the children of mothers rather than fathers with BP who had higher odds of not graduating primary education (OR 1.6). Lastly, child placement was associated with lower grades and lower graduation rates, and outcomes for children of parents with SMI were favorable compared with other children placed in care.
For children, parental SZ is associated with lower grades and lower chances for graduating primary education. In contrast, the children of parents with BP were indistinguishable from the reference group regarding school grades. This signifies that specificity of parental severe mental illness is important in relation to educational achievement of children.
精神分裂症(SZ)和双相情感障碍(BP)是全球范围内导致严重残疾的原因,父母的严重精神疾病(SMI)与儿童期逆境以及儿童的社会情感和认知问题有关。然而,父母的 BP 和 SZ 如何影响子女的受教育程度仍不清楚。
我们纳入了所有 1986 年至 1996 年期间在丹麦出生和生活的儿童(N=684.248)及其父母。我们的随访时间从 1986 年持续到 2014 年儿童毕业。主要结局变量是他们小学毕业后的学校成绩。学校成绩分为四类:未毕业、低绩点平均(GPA)、中 GPA 和高 GPA。然后,我们以中等 GPA 为参考类别,以没有 SZ 或 BP 的父母的子女为参考组,进行了多项逻辑回归分析。
与没有 SZ 或 BP 的父母的子女相比,SZ 父母的子女更有可能无法完成小学教育(OR2.6),并且 GPA 较低(OR1.6),高 GPA 的可能性较低(OR0.7)。此外,患有 BP 的母亲的子女比父亲的子女更有可能无法完成小学教育(OR1.6)。最后,儿童安置与较低的成绩和较低的毕业率相关,与其他接受照顾的儿童相比,SMI 父母的子女的结果较好。
对于儿童而言,父母的 SZ 与较低的成绩和较低的小学毕业率相关。相比之下,BP 父母的子女在学业成绩方面与参考组无明显差异。这表明父母严重精神疾病的特异性与儿童的教育成就有关。