Department of Chemistry, Institute of Technology Madras, Chennai-600036, India.
Org Biomol Chem. 2018 Jan 3;16(2):262-265. doi: 10.1039/c7ob02609a.
An efficient formal total synthesis of two compounds from the selaginpulvilin family of natural products, selaginpulvilin A and C, has been successfully achieved. The tetradehydro Diels-Alder (TDDA) reaction between an enyne and alkyne has been utilized for the creation of the necessary fluorene skeleton. Attempts at the conversion of selaginpulvilin A to selaginpulvilin B, F and H were unsuccessful.
已成功实现从天然产物卷柏素家族的两种化合物（卷柏素 A 和 C）的有效全合成。利用烯炔和炔之间的十四氢 Diels-Alder（TDDA）反应来构建必需的芴骨架。将卷柏素 A 转化为卷柏素 B、F 和 H 的尝试均未成功。
