Yoldez Houcine, Ahlem Blel, Abderrahim Ezzeddine, Faten Zeglaoui, Soumaya Rameh
Département d'anatomie et de cytologie pathologique, hôpital Charles-Nicolles, université El-Manar, 1006 Tunis, Tunisie.
Département d'anatomie et de cytologie pathologique, hôpital Charles-Nicolles, université El-Manar, 1006 Tunis, Tunisie.
Nephrol Ther. 2018 Feb;14(1):47-49. doi: 10.1016/j.nephro.2017.02.017. Epub 2017 Nov 26.
Nephrogenic systemic fibrosis is a rare entity occurred in patients with renal failure. It is related to toxicity to gadolinium, which is used as a contrast agent in magnetic resonance imaging. Clinic manifestations are variable. They begin by a thickening of the skin in the lower limbs and extending to the upper limbs. We report a new case of nephrogenic systemic fibrosis where cutaneous lesions begin in the upper right limb as indurated and ulcerated nodules. The diagnosis is histological.
肾源性系统性纤维化是一种发生于肾衰竭患者的罕见病症。它与钆的毒性有关，钆在磁共振成像中用作造影剂。临床表现多样。起初是下肢皮肤增厚，随后扩展至上肢。我们报告一例肾源性系统性纤维化新病例，其皮肤病变始于右上肢，表现为硬结和溃疡结节。诊断依靠组织学检查。
