Sperber G O
Bull Math Biol. 1989;51(2):275-86. doi: 10.1016/s0092-8240(89)80073-4.
In the commonly used model (Sokoloff) for the transport and metabolism of glucose and 2-deoxyglucose in brain tissue a novel choice of constant parameters is proposed. In particular the maximal transport capacity for glucose is assumed proportional to the rate of glucose consumption. The proportionality factor, the "transport factor", may be calculated from the lumped constant and is more likely than the latter to remain constant under varying conditions. Calculations founded on these considerations should yield results similar to the Sokoloff procedure in many situations, but differences appear when the arterial glucose concentration changes. The model is flexible and allows changes.
在脑组织中葡萄糖和2-脱氧葡萄糖的转运与代谢常用模型（索科洛夫模型）中，提出了一种新的常数参数选择。具体而言，假定葡萄糖的最大转运能力与葡萄糖消耗速率成正比。比例系数，即“转运系数”，可根据集总常数计算得出，并且在不同条件下比集总常数更有可能保持恒定。基于这些考虑进行的计算在许多情况下应能得出与索科洛夫方法相似的结果，但当动脉葡萄糖浓度变化时会出现差异。该模型具有灵活性，允许进行更改。
