Division of Pediatric Cardiology, Department of Pediatrics, University of California Los Angeles, Los Angeles, California, USA.
Division of Cardiology, Department of Medicine, Ahmanson/University of California Los Angeles Adult Congenital Heart Disease Center, Los Angeles, California, USA.
J Cardiovasc Electrophysiol. 2018 Mar;29(3):497-503. doi: 10.1111/jce.13404. Epub 2018 Jan 5.
The bidirectional Glenn operation for congenital heart disease produces anatomical constraints to conventional transvenous pacemaker implantation. An iliac approach, although not previously described in this population, is potentially a preferable alternative to a thoracotomy for epicardial pacing.
A single-center retrospective review was performed for all patients that underwent transvenous pacemaker implantation following the bidirectional Glenn operation with partial biventricular repair. Follow-up data, implant indications, and techniques were recorded. Five patients underwent a transvenous iliac approach (median age 26.9 years, interquartile range [IQR] 25.8-27.6). Pacing indications included AV block in 3 patients (2 requiring cardiac resychronization therapy) and sinus node dysfunction in 2. Implanted leads were atrial in 4 and ventricular in 3 (1 of the latter was placed in the coronary sinus). In two cases, transvenous leads were tunneled to a preexisting epicardial abdominal generator. Median follow-up was 4.1 years (range 1.0-16.7 years). One patient underwent device revision for lead position-related groin discomfort; a second patient developed atrial lead failure following a Maze operation and underwent lead replacement by the iliac approach. Patients were not routinely anticoagulated postprocedure given lead position in the subpulmonary circulation. At last follow-up, all patients were alive. One patient underwent heart transplantation 6 months after implant with only partial resolution of pacing-induced cardiomyopathy.
Trans-iliac pacemaker placement may be an effective alternative to surgery for patients requiring permanent pacing after the Glenn operation.
先天性心脏病的双向 Glenn 手术会对传统的经静脉起搏器植入造成解剖限制。虽然以前在该人群中没有描述过经髂动脉入路,但对于经胸心外膜起搏来说,它是一种潜在的替代开胸手术的方法。
对所有接受双向 Glenn 手术和部分双心室修复后进行经静脉起搏器植入的患者进行了单中心回顾性研究。记录了随访数据、植入指征和技术。5 名患者接受了经静脉髂动脉入路(中位年龄 26.9 岁,四分位距 [IQR] 25.8-27.6)。起搏指征包括 3 例房室传导阻滞(2 例需要心脏再同步治疗)和 2 例窦房结功能障碍。植入的导线 4 根为心房,3 根为心室(其中 1 根放置在冠状窦)。在 2 例患者中,经静脉导线被隧道到预先存在的心外膜腹部发生器。中位随访时间为 4.1 年(范围 1.0-16.7 年)。1 例患者因导线位置相关的腹股沟不适而行器械翻修;另 1 例患者在迷宫手术后发生心房导线故障,经髂动脉入路更换导线。由于导线位于肺动脉循环内,患者术后未常规抗凝。最后一次随访时,所有患者均存活。1 例患者在植入后 6 个月接受心脏移植,仅部分缓解起搏诱导性心肌病。
对于 Glenn 手术后需要永久性起搏的患者,经髂动脉起搏器放置可能是手术的有效替代方法。