Sueyoshi Kazuki, Sumiyoshi Tomiki
1 Department of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, Tokyo, Japan.
Clin EEG Neurosci. 2018 Jan;49(1):8-11. doi: 10.1177/1550059417745933.
Motivation is associated with electrophysiological markers, such as awake state delta oscillation and frontal alpha asymmetry, as well as event-related potentials, such as error-related negativity, feedback-related negativity, and prepulse inhibition. These indicators provide an objective measure of motivational deficits in psychiatric conditions, and response to treatment. Also, these modalities of brain activities are drawing attention as a target of neurofeedback training. The aim of this article is to provide a brief overview on electrophysiological findings relevant to the understanding of the mechanisms underlying impaired motivation in psychiatric disorders and clinical practice.
动机与电生理标志物相关，如清醒状态下的δ振荡和额叶α不对称性，以及事件相关电位，如错误相关负波、反馈相关负波和前脉冲抑制。这些指标为精神疾病中的动机缺陷以及治疗反应提供了客观的测量方法。此外，这些脑活动模式作为神经反馈训练的目标正受到关注。本文的目的是简要概述与理解精神疾病中动机受损机制及临床实践相关的电生理研究结果。
