Ghalleb Montassar, Bouzaiene Hatem, Slim Skander, Hadiji Achraf, Hechiche Monia, Ben Hassouna Jamel, Rahal Khaled
Surgical Oncology Department, Salah Azaiez Institute of Cancer, Tunis, Tunisia.
J Med Case Rep. 2017 Dec 17;11(1):350. doi: 10.1186/s13256-017-1516-8.
Malignant ovarian germ cell tumor is a rare type of disease, which generally has a good prognosis due to the high chemosensitivity of this type of tumor. Fertility preservation is an important issue because malignant ovarian germ cell tumor commonly affects young women. Although conservation is the standard for early stage, it becomes more debatable as the disease progresses to more advanced stages.
Report the case of a patient with an International Federation of Gynecology and Obstetrics Stage IIIc malignant ovarian germ cell tumor, who had conservative surgery and chemotherapy with a good fertility outcome.
A 23-year-old North African woman with a left malignant ovarian germ cell tumor stage IIIc was treated by left adnexectomy and omentectomy followed by chemotherapy. A 15-year follow-up showed no signs of relapse, and she completed three full-term natural pregnancies.
Malignant ovarian germ cell tumor is a rare ovarian tumor with a good prognosis. It is usually associated with a good fertility outcome in early stages. However, due to the rarity of the disease in advanced stages, the fertility outcome for this group of patients is not clear. This lack of data surrounding advanced stages points to the need for a meta-analysis of all published cases.
恶性卵巢生殖细胞肿瘤是一种罕见疾病，由于这类肿瘤具有高化疗敏感性，其总体预后通常较好。保留生育功能是一个重要问题，因为恶性卵巢生殖细胞肿瘤常影响年轻女性。尽管保留生育功能是早期患者的标准治疗方式，但随着疾病进展到更晚期，这一做法的争议性也更大。
报告一例国际妇产科联盟（FIGO）IIIc期恶性卵巢生殖细胞肿瘤患者，其接受了保守性手术及化疗，生育结局良好。
一名23岁的北非女性，患有左侧IIIc期恶性卵巢生殖细胞肿瘤，接受了左侧附件切除术和大网膜切除术，随后进行化疗。15年的随访显示无复发迹象，且她成功完成了三次足月自然妊娠。
恶性卵巢生殖细胞肿瘤是一种罕见的卵巢肿瘤，预后良好。早期通常生育结局良好。然而，由于晚期病例罕见，这组患者的生育结局尚不清楚。围绕晚期病例缺乏数据表明需要对所有已发表病例进行荟萃分析。
