Verga M C, Pastorino R, Casani A, Inturrisi F, de Waure C, Pugliese A, Dello Iacono I
Primary Care Pediatrics, ASL Salerno, C.so Umberto I, 103 84019 Vietri sul Mare (SA), Italy Phone: +39 089 761354 Fax: +39 089 761354 Cell: +39 338 3800 589 E-mail:
Department of Public Health, Section of Hygiene, Università Cattolica del Sacro Cuore, Rome, Italy.
Eur Ann Allergy Clin Immunol. 2017 Nov;49(6):270-275. doi: 10.23822/EurAnnACI.1764-1489.26.
Prevalence of the 's (AS) sensitization in children sensitized to (DP) is not known, neither it is to which percentage it might be due to cross-reactivity. The primary objective of the present retrospective cross-sectional study is to evaluate the prevalence of sensitization to AS in children sensitized or allergic to DP. Secondary outcomes were the prevalence of cross-reactivity and clinical relevance of the condition. The prevalence of sensitization to AS differs significantly among patients sensitized and not to DP (13.43% vs. 3.80%; p=0.019). The higher prevalence is mainly due to cross-reactivity with Der p10 (OR=8.86; 95% CI=4.33-40.74; p=0.0001). Currently, the sensitization to AS seems to have no clinical relevance in the pediatric population.
对粉尘螨（DP）致敏的儿童中屋尘螨（AS）致敏的患病率尚不清楚，也不知道其可能因交叉反应导致的比例。本回顾性横断面研究的主要目的是评估对DP致敏或过敏的儿童中对AS致敏的患病率。次要结果是交叉反应的患病率和该病症的临床相关性。对AS致敏的患病率在对DP致敏和未致敏的患者中存在显著差异（13.43%对3.80%；p=0.019）。较高的患病率主要归因于与Der p10的交叉反应（比值比=8.86；95%置信区间=4.33-40.74；p=0.0001）。目前，对AS的致敏在儿科人群中似乎没有临床相关性。
