Tóth Gábor, Sándor Gábor László, Gyenes Andrea, Tóth Jeannette, Seitz Berthold, Nagy Zoltán Zsolt, Szentmáry Nóra
Szemészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Üllői út 26., 1085.
II. Patológiai Intézet, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.
Orv Hetil. 2017 Dec;158(51):2011-2022. doi: 10.1556/650.2017.30939.
To summarize actual knowledge on epidemiology, etiology, pathology, clinical apparence and treatment of ocular surface squamous neoplasias. We summarize up-to-date literature on conjunctival intraepithelial neoplasia and invasive squamous cell carcinoma and present some own cases. Ocular surface squamous neoplasia is the most common malignant ocular surface tumor and the third most common ocular malignancy following malignant melanoma and lymphoma. In spite of its low malignant potential, in advanced stages it may reduce visual acuity significantly or even the eye globe has to be removed. In case of metastasis it may also be life-threatening. As local recurrences of ocular surface squamous neoplasias may occur, knowledge of intra- and postoperative adjuvant treatment options are indispensable and regular control examinations are necessary. Identification and adequate treatment of ocular surface squamous neoplasias are necessary in order to avoid its progression and to prevent recurrences. Orv Hetil. 2017; 158(51): 2011-2022.
总结关于眼表鳞状上皮肿瘤的流行病学、病因学、病理学、临床表现及治疗的实际知识。我们总结了关于结膜上皮内瘤变和浸润性鳞状细胞癌的最新文献，并展示了一些我们自己的病例。眼表鳞状上皮肿瘤是最常见的恶性眼表肿瘤，是继恶性黑色素瘤和淋巴瘤之后的第三大常见眼部恶性肿瘤。尽管其恶性潜能较低，但在晚期它可能会显著降低视力，甚至不得不摘除眼球。发生转移时也可能危及生命。由于眼表鳞状上皮肿瘤可能会局部复发，因此了解术中及术后辅助治疗方案必不可少，定期进行对照检查也很有必要。识别并充分治疗眼表鳞状上皮肿瘤对于避免其进展和预防复发是必要的。《匈牙利医学周报》2017年；158(51): 2011 - 2022。
