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一种从炭黑葡萄穗霉菌培养物中分离出的新型苯基螺二氢苊二聚体。

A novel phenylspirodrimane dimer from cultures of the fungus Stachybotrys chartarum.

作者信息

Ding Zhang-Gui, Zhao Jiang-Yuan, Ding Jian-Hai, Chunyu Wei-Xun, Li Ming-Gang, Gu Shao-Jie, Wang Fei, Wen Meng-Liang

机构信息

a Key Laboratory for Microbial Resources, Ministry of Education , Yunnan Institute of Microbiology, Yunnan University , Kunming , PR China.

b Engineering and Technology Research Center of Liupanshan Resources, College of Chemistry and Chemical Engineering , Ningxia Normal University , Guyuan , PR China.

出版信息

Nat Prod Res. 2018 Oct;32(19):2370-2374. doi: 10.1080/14786419.2017.1413565. Epub 2017 Dec 18.

Abstract

Stachartone A (1), a novel phenylspirodrimane dimer, was isolated from cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Its structure was elucidated by means of spectroscopic methods. At the same time, compound (1) was tested for its cytotoxicity against five human cancer cell lines.

摘要

柱孢酮A(1)是一种新型的苯基螺二氢萘二聚体,从与锡矿尾矿相关的真菌炭疽菌的培养物中分离得到。其结构通过光谱方法得以阐明。同时,对化合物(1)针对五种人类癌细胞系的细胞毒性进行了测试。

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